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ProteomicsDisulfide mapping of J-chain by crosslinking MS
Here we show how J-chain (JC) outcompetes the sixth IgM subunit during assembly. We looked at the disulfide re-arrangements in JC and showed that it exists as an unstructured protein with non-native disulfides before its insertion into IgM.
ORGANISM(S): Mus musculus (Mouse) 
2024-12-04 | PXD048614 | Pride
Disulfide J-chain Crosslinking 
UnknownHow J-chain ensures the assembly of immunoglobulin IgM pentamers.
Not available
S-EPMC11729874 | biostudies-literature
UnknownThe J-shape of β2GPI reveals a cryptic discontinuous epitope across domains I and II.
Not available
S-EPMC12398265 | biostudies-literature
ProteomicsA novel mobile genomic island: introducing ‘cephalosporinase morons’ in Enterobacteriaceae
The exchange of mobile genomic islands (MGIs) between microorganisms is often mediated by phages. As a consequence, not only phage genes are transferred, but also genes that have no particular function in the phage's lysogenic cycle. If they provide benefits to the phage's host, such genes are refer...
ORGANISM(S): Enterobacter cloacae 
2018-08-21 | PXD007113 | Pride
"cephalosporin resistance " Enterobacteriaceae "mobile genomic islands " 
TranscriptomicsExpression analysis of colorectal carcinoma cells with defunct P53 (D53wt cells)
Whole transcriptome expression analysis of colorectal carcinoma cells with defunct P53 on Affymetrix Human Tiling 1.0 array set. Transcriptome-wide expression data was assessed by using TileShuffle (Otto C, Reiche K, Hackermüller J. "Detection of differentially expressed segments in tiling array dat...
ORGANISM(S): Homo sapiens 
2014-02-04 | GSE43912 | GEO
TranscriptomicsExpression analysis of INA6 cells permanently cultured in presence of IL-6
Whole transcriptome expression analysis of INA6 cells on Affymetrix Human Tiling 1.0 array set. Cells have been permanently cultured in presence of IL-6. Transcriptome-wide expression data was assessed by using TileShuffle (Otto C, Reiche K, Hackermüller J. "Detection of differentially expressed seg...
ORGANISM(S): Homo sapiens 
2014-02-04 | GSE44658 | GEO
TranscriptomicsExpression analysis of HFF cells in G2 phase
Whole transcriptome expression analysis of HFF cells on Affymetrix Human Tiling 1.0 array set. Cells were synchronised by serum starvation and transcriptome-wide expression in G2 phase was assessed by using TileShuffle (Otto C, Reiche K, Hackermüller J. "Detection of differentially expressed segment...
ORGANISM(S): Homo sapiens 
2014-02-04 | GSE44630 | GEO
TranscriptomicsExpression analysis of HFF cells in S phase
Whole transcriptome expression analysis of HFF cells on Affymetrix Human Tiling 1.0 array set. Cells were synchronised by serum starvation and transcriptome-wide expression in S phase was assessed by using TileShuffle (Otto C, Reiche K, Hackermüller J. "Detection of differentially expressed segments...
ORGANISM(S): Homo sapiens 
2014-02-04 | GSE44629 | GEO
TranscriptomicsExpression analysis of HFF cells in G1 phase
Whole transcriptome expression analysis of HFF cells on Affymetrix Human Tiling 1.0 array set. Cells were synchronised by serum starvation and transcriptome-wide expression in G1 phase was assessed by using TileShuffle (Otto C, Reiche K, Hackermüller J. "Detection of differentially expressed segment...
ORGANISM(S): Homo sapiens 
2014-02-04 | GSE44628 | GEO
TranscriptomicsExpression analysis of HFF cells in G0 phase
Whole transcriptome expression analysis of HFF cells on Affymetrix Human Tiling 1.0 array set. Cells were synchronised by serum starvation and transcriptome-wide expression in G0 phase was assessed by using TileShuffle (Otto C, Reiche K, Hackermüller J. "Detection of differentially expressed segment...
ORGANISM(S): Homo sapiens 
2014-02-04 | GSE44627 | GEO
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