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TranscriptomicsIdentification of Novel Therapeutic Targets in Microdissected Clear Cell Ovarian Cancers
To identify the gene signature accounting for the distinct clinical outcomes in ovarian clear cell cancer patients Clear cell ovarian cancer is an epithelial ovarian cancer histotype that is less responsive to chemotherapy and carries poorer prognosis than serous and endometrioid histotypes. Despite...
ORGANISM(S): Homo sapiens 
2011-05-24 | E-GEOD-29450 | biostudies-arrayexpress
ProteomicsProtease activity profiling of ovarian clear cell carcinoma
Ovarian clear cell carcinoma (OCCC) is an understudied poor prognosis subtype of ovarian cancer lacking in effective molecularly targeted therapies; efforts to define drivers of OCCC malignancy may lead to new therapeutic targets and approaches. Among potential targets are secreted proteases, enzyme...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-05-07 | MSV000087385 | MassIVE
ProteomicsThe proteome of clear cell ovarian carcinoma
Clear cell ovarian carcinoma (CCOC) is the second most common subtype of epithelial ovarian carcinoma. Late stage CCOC is not responsive to gold-standard chemotherapy and result in suboptimal outcome for patients. In-depth molecular insight is urgently needed to stratify the disease and drive therap...
ORGANISM(S): Homo sapiens (Human) 
2022-09-02 | PXD032355 | Pride
Ovarian carcinoma Tmt Clear cell 
ProteomicsP53 IP-MS in Ovarian clear cell carcinoma
Ovarian cancer (OC) is a highly fatal and refractory malignancy affecting women, with platinum resistance remaining a major clinical dilemma. Ovarian clear cell carcinoma (OCCC) frequently exhibits increased platinum refractoriness than the other OC subtypes, accompanied by heightened glycogen that ...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD057846 | Pride
Ip-ms Ovarian clear cell carcinoma P53 
TranscriptomicsExpression data from ovarian cancer cell lines
Ovarian clear cell carcinoma (OCCC) shows unique clinical features including an association with endometriosis and poor prognosis. We previously reported that the contents of endometriotic cysts, especially high concentrations of free iron, are a possible cause of OCCC carcinogenesis through iron-in...
ORGANISM(S): Homo sapiens 
2011-05-16 | E-GEOD-29175 | biostudies-arrayexpress
ProteomicsGlobal Proteomic Analysis of Ovarian Clear Cell Carcinoma Cells Lacking ARID1A Reveals Upregulated Mitochondrial Electron Transport Chain Activity
Ovarian clear cell carcinoma (OCCC) is the most lethal gynecological cancer. It is characterized by somatic inactivating mutations of ARID1A, a component of the SWI/SNF chromatin-remodeling complex, occurring in up to 70% of patients. Patients with these mutations in their tumors have considerably p...
ORGANISM(S): Homo sapiens (Human) 
2025-07-07 | PXD050332 | Pride
Mitochondrial electron transport chain Mitochondria Arid1a Ovarian clear cell carcinoma 
TranscriptomicsExpression data from high-grade serous ovarian carcinomas (HGSC), clear cell ovarian carcinomas (CCC) and ovarian surface epithelium (OSE)
Background: The aim of this study was to identify differentially expressed miRNAs in high-grade serous ovarian carcinoma (HGSC), clear cell ovarian carcinoma (CCC) and ovarian surface epithelium (OSE). Selected miRNAs were evaluated for association with clinical parameters including survival, and mi...
ORGANISM(S): Homo sapiens 
2014-02-13 | E-GEOD-47841 | biostudies-arrayexpress
ProteomicsThe IP-MS analysis of anti-p53 and anti-GYS1 in ovarian clear cell carcinoma
Ovarian cancer (OC) is a highly fatal and refractory malignancy affecting women, with platinum resistance remaining a major clinical dilemma. Ovarian clear cell carcinoma (OCCC) frequently exhibits increased platinum refractoriness than the other OC subtypes, accompanied by heightened glycogen that ...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD057878 | Pride
Gys1 Ip-ms Ovarian clear cell carcinoma P53 
GenomicsWhole-exome sequencing of ovarian clear cell carcinoma in clinical outliers
Whole-exome sequencing dataset for the Australian Ovarian Cancer Study (AOCS) and The Jikei University School of Medicine (JIKEI) ovarian clear cell carcinoma (OCCC) clinical outliers project, representing 10 donors. Although OCCC are commonly resistant to platinum based chemotherapy, good clinical ...
EGAS00001004248 | EGA
TranscriptomicscaArray_cho-00156: Gene Expression in Ovarian Cancer Reflects Both Morphology and Biological Behavior
Biologically and clinically meaningful tumor classification schemes have long been sought. Some malignant epithelial neoplasms, such as those in the thyroid and endometrium, exhibit more than one pattern of differentiation, each associated with distinctive clinical features and treatments. In other ...
ORGANISM(S): Homo sapiens 
2015-05-07 | E-GEOD-68600 | biostudies-arrayexpress
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