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RNA-seq of human cancer cell line OVCA420* following TIGAR knockdown with shRNA
RNA-seq of PRSS23 knockdown in ovarian cancer cell lines JHOC-5 and OVCA420
Bulk RNA-seq was performed in ovarian cancer cell lines JHOC-5 and OVCA420 after lentiviral PRSS23 knockdown using two independent shRNAs (shRNA_30 and shRNA_46) or a non-targeting shRNA control. Gene-level read counts for all samples are provided.
ORGANISM(S): Homo sapiens 
2026-01-07 | GSE315399 | GEO
To identify differentially expressed genes following TIGAR knockdown, OVCA420* was transduced with TIGAR-targeting or non-targeting (control) shRNAs. 54 hours after the transduction, RNA was extracted and Illumina TruSeq RNA Sample Preparation Kit v2 was used to prepare the libraries. Each group con...
ORGANISM(S): Homo sapiens 
Claudins are tight junction proteins that are involved in tight junction formation and function. Previous studies have shown that claudin-7 is frequently upregulated in epithelial ovarian cancer (EOC) along with claudin-3 and claudin-4. Here, we investigate in detail the expression patterns of claud...
ORGANISM(S): Homo sapiens 
Recent findings show that EMT in cancer is dynamic and display a number of intermediate stages along the transition to obtain a high phenotypic and functional cellular plasticity. To comprehend transcriptional regulation among major EMT-transcription factors (EMT-TFs) along the EMT spectrum, we perf...
ORGANISM(S): Homo sapiens 
2022-05-25 | GSE145553 | GEO
Genomics
Effect of ZNF217 overexpression on ovarian cancer cells
Genomics
Effect of ZNF217 knockdown in ovarian cancer cells
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