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UnknownRadical Generation from the Gas-Phase Activation of Ionized Lipid Ozonides.
Not available
S-EPMC5486690 | biostudies-literature
UnknownHighly active ozonides selected against drug resistant malaria.
Not available
S-EPMC4957497 | biostudies-literature
UnknownInhibition of Cytomegalovirus Replication with Extended-Half-Life Synthetic Ozonides.
Not available
S-EPMC6325236 | biostudies-literature
UnknownCharacterization of Pure Ozonides from Ozonolysis of Oleic Acid Methyl Ester; Use of a Protocol for the Analysis of the Corresponding Stable Ozonides from Triolein and Organic Extra Virgin Olive Oil (+OIL<sup>®</sup>).
Not available
S-EPMC11819892 | biostudies-literature
UnknownMonoclonal Antibodies That Recognize the Alkylation Signature of Antimalarial Ozonides OZ277 (Arterolane) and OZ439 (Artefenomel).
Not available
S-EPMC4718528 | biostudies-literature
UnknownAnti-malarial ozonides OZ439 and OZ609 tested at clinically relevant compound exposure parameters in a novel ring-stage survival assay.
Not available
S-EPMC6918666 | biostudies-literature
UnknownStability of Terpenoid-Derived Secondary Ozonides in Aqueous Organic Media.
Not available
S-EPMC9393869 | biostudies-literature
ProteomicsComparison of the proteome-wide alkylation signatures of antimalarial peroxides: ozonides vs. artemisinin
Antimalarial peroxides such as the phytochemical artemisinin or the synthetic artefenomel are activated by reductive cleavage of the peroxide bond. This happens inside the malaria parasite, presumably in the food vacuole with ferrous heme as the electron donor. The generated carbon-centered radicals...
ORGANISM(S): Plasmodium falciparum NF135/5.C10 
2022-02-24 | PXD010264 | Pride
Malaria Label-free quantification Peroxides 
ProteomicsPeroxide antimalarial drugs impact redox homeostasis in Plasmodium falciparum infected red blood cells
Plasmodium falciparum causes the most lethal form of malaria. The frontline treatments for this severe disease are combination therapies based on semisynthetic peroxide antimalarials, known as artemisinins. There is growing resistance to artemisinins and new drugs with novel mechanisms of action are...
ORGANISM(S): Homo sapiens (Human) Plasmodium falciparum 
2022-02-17 | PXD027334 | Pride
Plasmodium falciparum Malaria Redox homeostasis Peroxides Glutathione. Ozonides 
UnknownBridged 1,2,4-Trioxolanes: SnCl4-Catalyzed Synthesis and an In Vitro Study against S. mansoni.
Not available
S-EPMC10343456 | biostudies-literature
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