Sort   by:  
 Page size 
TranscriptomicsPost-transcriptional regulation of cell-cell interaction protein-encoding transcripts by Zfs1p in S. pombe
Members of the tristetraprolin (TTP) family of CCCH tandem zinc finger proteins can bind directly to AU-rich elements in mRNAs and promote transcript deadenylation and decay. The yeast Schizosaccharomyces pombe expresses a single TTP family member, Zfs1p, that has been linked to the mating response...
ORGANISM(S): Schizosaccharomyces pombe 
2012-11-06 | E-GEOD-35009 | biostudies-arrayexpress
TranscriptomicsGlobal analysis of mRNA isoform half-lives: identification of stabilizing and destabilizing elements in yeast
We measured half-lives of 21,248 mRNA 3’ isoforms in yeast by rapidly depleting RNA polymerase II from the nucleus and performing direct RNA sequencing throughout the decay process. Interestingly, the half-lives of mRNA isoforms from the same gene, including nearly identical isoforms, often vary wid...
ORGANISM(S): Saccharomyces cerevisiae 
2014-04-02 | E-GEOD-52286 | biostudies-arrayexpress
TranscriptomicsPost-transcriptional regulation of cell-cell interaction protein-encoding transcripts by Zfs1p in S. pombe (RNA-Seq)
Members of the tristetraprolin (TTP) family of CCCH tandem zinc finger proteins can bind directly to AU-rich elements in mRNAs and promote transcript deadenylation and decay. The yeast Schizosaccharomyces pombe expresses a single TTP family member, Zfs1p, that has been linked to the mating response...
ORGANISM(S): Schizosaccharomyces pombe 
2012-11-06 | E-GEOD-35376 | biostudies-arrayexpress
TranscriptomicsRNA sequencing of circulating tumour cells implicates WNT signaling in pancreatic cancer metastasis (mouse data)
Circulating tumour cells (CTCs) shed into blood from primary cancers include putative precursors that initiate distal metastases. While these cells are extraordinarily rare, they may identify cellular pathways contributing to the blood-borne dissemination of cancer. Here, we adapted a microfluidic d...
ORGANISM(S): Mus musculus 
2012-08-17 | E-GEOD-40171 | biostudies-arrayexpress
TranscriptomicsRNA sequencing of circulating tumour cells implicates WNT signaling in pancreatic cancer metastasis (human data)
Circulating tumour cells (CTCs) shed into blood from primary cancers include putative precursors that initiate distal metastases. While these cells are extraordinarily rare, they may identify cellular pathways contributing to the blood-borne dissemination of cancer. Here, we adapted a microfluidic d...
ORGANISM(S): Homo sapiens 
2012-08-17 | E-GEOD-40174 | biostudies-arrayexpress
Sort   by:  
 Page size