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TranscriptomicsGene expression profile of right ventricles from adult wild type and Ezh2-deficient hearts
Adult-onset diseases can be associated with in utero events, but mechanisms for this remain unknown. The polycomb histone methyltransferase, Ezh2, stabilizes transcription by depositing repressive marks during development that persist into adulthood, but its function in postnatal organ homeostasis i...
ORGANISM(S): Mus musculus 
2011-12-09 | E-GEOD-34274 | biostudies-arrayexpress
MetabolomicsAlterations in the tyrosine and phenylalanine pathways revealed by biochemical profiling in cerebrospinal fluid of Huntington’s disease subjects
Huntington's disease (HD) is a severe neurological disease leading to psychiatric symptoms, motor impairment and cognitive decline. The disease is caused by a CAG expansion in the huntingtin (HTT) gene, but how this translates into the clinical phenotype of HD remains elusive. Using liquid chromatog...
2019-06-21 | MTBLS749 | MetaboLights
UnknownImproving route development using convergent retrosynthesis planning.
Not available
S-EPMC11869726 | biostudies-literature
ProteomicsHX mapping of the binding interface between a DCP and murine LRRC-15
This dataset is associated with the manuscript titled: Development and Structural Characterization of LRRC15-binding Disulfide-Constrained Peptides for Enhanced Tumor Imaging Authors: Benjamin J. Tombling, Fei Cai, Tim Wendorff, Annie Ogasawara, Herman S. Gill, Jeff N. Tinianow, Andrew Chang, Aaron ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2026-02-20 | MSV000100920 | MassIVE
UnknownDevelopment and validation of an integrated DNA walking strategy to detect GMO expressing cry genes.
Not available
S-EPMC6020286 | biostudies-literature
UnknownMultitarget transcranial direct current stimulation for freezing of gait in Parkinson's disease.
Not available
S-EPMC5964604 | biostudies-literature
MetabolomicsMass spectrometry based metabolomics for in vitro systems pharmacology: Pitfalls, challenges, and computational solutions

INTRODUCTION: Mass spectrometry based metabolomics has become a promising complement and alternative to transcriptomics and proteomics in many fields including in vitro systems pharmacology. Despite several merits, metabolomics based on liquid chromatography mass spectrometry (LC...

2017-08-23 | MTBLS401 | MetaboLights
MetabolomicsIntegration of magnetic resonance imaging and protein and metabolite CSF measurements to enable early diagnosis of secondary progressive multiple sclerosis

Molecular networks in neurological diseases are complex. Despite this fact, contemporary biomarkers are in most cases interpreted in isolation, leading to a significant loss of information and power. We present an analytical approach to scrutinize and combine information from biomarkers originati...

2018-08-13 | MTBLS558 | MetaboLights
UnknownUse of Whole Genome Sequencing Data for a First in Silico Specificity Evaluation of the RT-qPCR Assays Used for SARS-CoV-2 Detection.
Not available
S-EPMC7432934 | biostudies-literature
UnknownDeepening of In Silico Evaluation of SARS-CoV-2 Detection RT-qPCR Assays in the Context of New Variants.
Not available
S-EPMC8069896 | biostudies-literature
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