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MetabolomicsPenicillium-Mediated Toxicity and Microbial Dysbiosis Are Associated with Fruiting Body Abortion in Artificially Cultivated Ophiocordyceps sinensis

The Chinese caterpillar fungus, Ophiocordyceps sinensis, is a valuable medicinal entomopathogenic fungus, but artificial cultivation is hindered by fruiting body abortion, severely impacting yield and quality. The interactions between the fungus, its host insects, and soil are critical for its de...

2026-06-24 | MTBLS14844 | MetaboLights
MetabolomicsPlasma non-targeted metabolome of high- and low-body-weight broilers

In large-scale poultry farming, broilers of the same breed share a common genetic background and identical management conditions, yet substantial individual variation in body weight persists. In this study, we identified distinct plasma proteomic profiles between high and low weight broilers, wit...

2025-06-10 | MTBLS12390 | MetaboLights
MetabolomicsIntegration of whole-body [18F]FDG PET/MRI with non-targeted metabolomics can provide new insights on tissue-specific insulin resistance in type 2 diabetes
Alteration of various metabolites has been linked to type 2 diabetes (T2D) and insulin resistance. However, identifying significant associations between metabolites and tissue-specific phenotypes requires a multi-omics approach. In a cohort of 42 subjects with different levels of glucose tolerance (...
2020-01-06 | MTBLS1051 | MetaboLights
MetabolomicsDysregulated high-density lipoprotein and low-density lipoprotein subfractions increase metabolic dysfunction-associated steatotic liver disease risk: A study of patients across body mass index categories

Background: To investigate biomarker differences among patients with metabolic dysfunction-associated steatotic liver disease (MASLD) across body mass index (BMI) types, we analyzed clinical data from 2,013 subjects and serum samples from 402 patients. The clinical characteristic...

2026-02-05 | MTBLS13821 | MetaboLights
MetabolomicsAnalysis of the human adult urinary metabolome variations with age, body mass index and gender by implementing a comprehensive workflow for univariate and OPLS statistical analyses. ('Sacurine' data set)

Urine metabolomics is widely used for biomarker research in the fields of medicine and toxicology. As a consequence, characterization of the variations of the urine metabolome under basal conditions becomes critical in order to avoid confounding effects in cohort studies. Such physiological infor...

2017-01-20 | MTBLS404 | MetaboLights
ProteomicsP-body proteome
LC-MS/MS was conducted to characterize the proteome of P-bodies in HeLa cells.
ORGANISM(S): Homo sapiens (Human) 
2023-10-12 | PXD034559 | Pride
Human P-body 
GenomicsEDC4 C-terminal domain scaffolds P-body assembly and links P-body dynamics to p53 mediated tumor suppression
EDC4 C-terminal domain scaffolds P-body assembly and links P-body dynamics to p53 mediated tumor suppression
PRJNA1164755 | ENA
ProteomicsThe proteome of normal human iris, ciliary body, retinal pigment epithelium, and choroid
The iris is a fine structure that controls the amount of light that enters the eye. The ciliary body controls the shape of the lens and produces aqueous humor. The retinal pigment epithelium and choroid (RPE/choroid) are essential in supporting the retina and absorbing light energy that enters the e...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-11-29 | MSV000081766 | MassIVE
TranscriptomicsComparison of the human oocyte to its sister polar body
Clinicians need additional metrics for predicting quality of human oocytes for IVF procedures. Human polar bodies reflect the oocyte transcript profile. Quantitation of polar body mRNAs could allow for both oocyte ranking and embryo preferences in IVF applications. The transcriptome of a polar body ...
ORGANISM(S): Homo sapiens 
2011-10-12 | E-GEOD-32689 | biostudies-arrayexpress
GenomicsRNA sequestration in P-bodies sustains myeloid leukemia [P-body-seq]
RNA sequestration in P-bodies sustains myeloid leukemia [P-body-seq]
PRJNA932348 | ENA
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