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LC-MS/MS was conducted to characterize the proteome of P-bodies in HeLa cells.
ORGANISM(S): Homo sapiens (Human) 
2023-10-12 | PXD034559 | Pride
EDC4 C-terminal domain scaffolds P-body assembly and links P-body dynamics to p53 mediated tumor suppression
Post-transcriptional RNA regulation is critical for the formation of primordial follicles, which determine female reproductive potential. Stress-induced disruptions in RNA metabolism are increasingly recognized as key factors impairing oogenesis, but the underlying mechanisms remain poorly understoo...
ORGANISM(S): Mus musculus (Mouse) 
2026-09-07 | PXD058281 | Pride
DCPS modulates TDP-43 mediated neurodegeneration through P-body regulation [ARTR-seq]
DCPS modulates TDP-43 mediated neurodegeneration through P-body regulation [RNA-seq]
Hallacli E, Kayatekin C, Nazeen S, Wang XH, Sheinkopf Z, Sathyakumar S, Sarkar S, Jiang X, Dong X, Di Maio R, Wang W, Keeney MT, Felsky D, Sandoe J, Vahdatshoar A, Udeshi ND, Mani DR,Carr SA, de Jager P, Myers CL, Lindquist S, Greenmyre TJ, Bartel DP, Feany MB, Sunyaev S, Chung CY and Khurana V. Alp...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-03-09 | MSV000089026 | MassIVE
Processing bodies (P-bodies) are membrane-less organelles involved in mRNA metabolism, including decay, storage, and translational repression. Their formation is driven by liquid-liquid phase separation, primarily mediated by the scaffold protein EDC4. This study identifies the C-terminal domain of ...
ORGANISM(S): Homo sapiens 
2025-05-31 | GSE277915 | GEO
Identification of interactors of Arabidopsis P-body components DCP1 and DCP5 in Col-0 and atg5-1 Arabidopsis thaliana plants by IP-MSMS, and in transiently transformed Nicotiana benthamiana by proximity labeling.
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) Nicotiana benthamiana Pseudomonas syringae pv. tomato 
2026-03-17 | PXD074949 | Pride
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