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Unknownp190-B RhoGAP regulates the functional composition of the mesenchymal microenvironment.
Not available
S-EPMC3919554 | biostudies-literature
TranscriptomicsRetroviral transduction of CD34+ cells with P190 and P210 BCR/ABL1 fusion genes
Expression of P190 and P210 BCR/ABL1 in normal human CD34(+) cells induces similar gene expression profiles and results in a STAT5-dependent expansion of the erythroid lineage The P190 and P210 BCR/ABL1 fusion genes are mainly associated with different types of hematologic malignancies, but it is pr...
ORGANISM(S): Homo sapiens 
2009-05-12 | GSE16042 | GEO
ProteomicsAltered growth and molecular features of Jurkat cells after introduction of the BCR-ABL1 p190 gene fusion
The Philadelphia Chromosome is the result of a balanced reciprocal translocation be-tween the long arms of chromosomes 9 and 22, resulting in the fusion gene BCR-ABL1. Despite its being a hallmark of acute lymphocytic leukemia (ALL), acute myelogenous leukemia (AML) and mixed-phenotype acute leukemi...
ORGANISM(S): Homo sapiens (Human) 
2026-02-23 | PXD071195 | Pride
Jurkat Bcr-abl1 P190 All 
TranscriptomicsDifferential gene expression analysis of WT and p190-B-/- HSC after bone marrow transplantation
The overall goals are these experiments are to identify genes and pathways that are critical for hematopoietic stem cell functions during bone marrow regeneration after transplantation. We have found that loss of expression of p190-B RhoGAP, a negative regulator of RhoGTPase, enhances HSC long-term ...
ORGANISM(S): Mus musculus 
2016-11-14 | GSE89794 | GEO
UnknownDifferential signaling networks of Bcr-Abl p210 and p190 kinases in leukemia cells defined by functional proteomics.
Not available
S-EPMC5508078 | biostudies-literature
MetabolomicsMetabolomics of human primary B-ALL cells treated by BCR-Abl1 inhibitor, STI571, and p190 BCR-Abl+ BAF3 cells with ASS1 knockdown
Analyze the Metabolomics changes in B-ALL cells after the treatment of imatinib and p190+ BAF3 cells with ASS1 knockdown or left untreated. two methods as the below LC-MS description showed were used.
2026-07-08 | MTBLS14638 | MetaboLights
UnknownPARP1 Characterization as a Potential Biomarker for BCR::ABL1 p190+ Acute Lymphoblastic Leukemia.
Not available
S-EPMC10705790 | biostudies-literature
Unknownp190-B RhoGAP and intracellular cytokine signals balance hematopoietic stem and progenitor cell self-renewal and differentiation.
Not available
S-EPMC5309857 | biostudies-literature
UnknownJak2/STAT6/c-Myc pathway is vital to the pathogenicity of Philadelphia-positive acute lymphoblastic leukemia caused by P190BCR-ABL.
Not available
S-EPMC9887777 | biostudies-literature
UnknownDevelopment and evaluation of armored RNA-based standards for quantification of BCR-ABL1p210/p190 fusion gene transcripts.
Not available
S-EPMC6816845 | biostudies-literature
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