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GenomicsChIP-Seq of human H1299 lung carcinoma cells - genomic location data for ectopic p73
The integral role of p53 in tumor suppression has promted many laboratories to perform extensive analyses of signaling pathways downstream of the p53 family of sequence-specific DNA binding transcription factors (p53 and its homologs p63 and p73). Despite the ability of p73 to regulate many p53 fam...
ORGANISM(S): Homo sapiens 
2009-08-30 | E-GEOD-11672 | biostudies-arrayexpress
Transcriptomicsp53 and p73 ChIP-chip experiments in HCT116-3(6) cells
The p53-family of transcription factors share a highly homologous DNA binding domain and have overlapping and distinct biological functions. Using chromatin immunoprecipitation in combination with NimbleGen promoter arrays and a Model-based Algorithm for Promoter arrays (MAP), we performed a direct ...
ORGANISM(S): Homo sapiens 
2009-06-30 | E-GEOD-12224 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human p73 over-expressing H1299 cells
The integral role of p53 in tumor suppression has promted many laboratories to perform extensive analyses of signaling pathways downstream of the p53 family of sequence-specific DNA binding transcription factors (p53 and its homologs p63 and p73). Despite the ability of p73 to regulate many p53 fam...
ORGANISM(S): Homo sapiens 
2008-10-20 | E-GEOD-11626 | biostudies-arrayexpress
ProteomicsAcetylation of p73 in 293T cell
293T cells ectopically expressing FLAG-tagged p73 were treated with AGK2 and p73 was immunoprecipitated. The precipitants were resuspended in deacetylation buffer (50 mM Tris-HCl pH 8.0, 140 mM NaCl, 2 mM MgCl 2 ) and incubated with recombinant SIRT2 protein (10 U). The reaction was terminated by bo...
ORGANISM(S): Homo Sapiens (human) 
2018-09-10 | PXD010411 | JPOST Repository
TranscriptomicsTranscription profiling of mouseB-cell lymphomas with defined genetic alterations in p53 or p73
Induction of apoptosis by the tumor suppressor p53 is known to protect from Myc-driven lymphomagenesis. The p53 family member p73 is also a pro-apoptotic protein, which is activated in response to oncogenes like Myc. We therefore investigated whether p73 provides a similar protection from Myc-driven...
ORGANISM(S): Mus musculus 
2008-12-05 | E-MEXP-1620 | biostudies-arrayexpress
TranscriptomicsExpression data from rapamycin treatment and/or p73 knock-down in Rh30 cells
p73 is a p53 family transcription factor that plays critical roles during development and tumor suppression. We analyzed p73 activity using a combination of ChIP-on-Chip and gene expression profiling, both at baseline and after treatment with the mTOR inhibitor rapamycin. We generated an mTOR-p73 g...
ORGANISM(S): Homo sapiens 
2011-01-05 | E-GEOD-15703 | biostudies-arrayexpress
GenomicsCeleribacter indicus strain:P73
Celeribacter indicus strain:P73 Genome sequencing
PRJNA170415 | ENA
GenomicsPseudomonas syringae strain:P73
Pseudomonas syringae strain P73 genome sequencing and assembly
PRJNA555018 | ENA
GenomicsClostridioides difficile P73
Clostridioides difficile P73 Genome sequencing and assembly
PRJNA86051 | ENA
GenomicsClostridioides difficile strain:703-P73
Clostridioides difficile strain:703-P73 Genome sequencing and assembly
PRJNA376253 | ENA
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