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TranscriptomicsTranscription profiling of mouse macrophaes and mast cells from Pac1+/+ versus Pac1-/- animals
This SuperSeries is composed of the following subset Series:; GSE3993: Pac1+/+ versus Pac1-/- TG-macrophages_LPS 6h; GSE3994: Pac1+/+ versus Pac1-/- BMMCs_IgE-DNP 2 h Experiment Overall Design: Refer to individual Series
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-4014 | biostudies-arrayexpress
ProteomicsIdentification of PAC1 interactome in activated T cells
To examine the molecular mechanisms by which PAC1 suppresses T cell response to antigen, we conducted immunoprecipitation followed by mass spectrometry to characterize PAC1-associated proteins in activated T cells
ORGANISM(S): Homo sapiens (Human) 
2020-01-07 | PXD012201 | Pride
Pac1 T cells Interactome 
TranscriptomicsTranscription profiling of mouse Pac1+/+ versus Pac1-/- TG-macrophages treated with LPS - 6h
LPS-stimulated macrophages from Pac1+/+ and Pac1-/- mice were compared to assess gene expression changes in the absence of PAC-1 (also known as Dual specificity phosphatase 2). Experiment Overall Design: Age matched Pac1+/+ and Pac1-/- littermates were used to obtain equal numbers of thiolycollate-e...
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-3993 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse bone marrow-derived mast cells were differentiated over 4-6 weeks using bone marrow from Pac-1+/+ and Pac1-/- littermate animals
Bone marrow-derived mast cells were differentiated over 4-6 weeks using bone marrow from Pac-1+/+ and Pac1-/- littermate mice. Cell purity was 99% c-kit and Fc epsilon receptor positive as assessed by flow cytometry. Cells were stimulated by Fc epsilon receptor crosslinking using IgE-DNP/HSA for sen...
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-3994 | biostudies-arrayexpress
TranscriptomicsPac1+/+ versus Pac1-/- TG-macrophages_LPS 6h
LPS-stimulated macrophages from Pac1+/+ and Pac1-/- mice were compared to assess gene expression changes in the absence of PAC-1 (also known as Dual specificity phosphatase 2). Keywords: Comparison of Pac1+/+ with Pac1-/- activated macrophages
ORGANISM(S): Mus musculus 
2006-01-10 | GSE3993 | GEO
GenomicsPac1+/+ versus Pac1-/- in macrophages and mast cells
Pac1+/+ versus Pac1-/- in macrophages and mast cells
PRJNA95111 | ENA
GenomicsMus musculus
Pac1+/+ versus Pac1-/- TG-macrophages_LPS 6h
PRJNA104885 | ENA
GenomicsRNAseq analysis of differentiated rat PAC1 pulmonary artery smooth muscle cells (SMCs) compared to proliferative cells, and the RBPMS knockdown and MBNL1&2 knockdown in differentiated PAC1 cells.
RNAseq analysis of differentiated rat PAC1 pulmonary artery smooth muscle cells (SMCs) compared to proliferative cells, and the RBPMS knockdown and MBNL1&2 knockdown in differentiated PAC1 cells.
PRJNA1287758 | ENA
UnknownPositive allosteric regulation of PAC1-R up-regulates PAC1-R and its specific ligand PACAP.
Not available
S-EPMC9828401 | biostudies-literature
GenomicsChIP-seq analysis of wild-type or PAC1-/- T cells with anti-H3K27-ac
ChIP-seq analysis of wild-type or PAC1-/- T cells with anti-H3K27-ac
PRJNA592972 | ENA
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