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TranscriptomicsGene expression profile of primary human naive and memory CD4+ T lymphocytes.
Gene expression data of primary human naive and memory CD4+T lymphocytes purified from peripheral blood are generated to be analyzed in different ways such as for traditional searching of differentially expressed genes between the two cell subsets or in combination to in-silico data of microRNAs tar...
ORGANISM(S): Homo sapiens 
2011-06-26 | E-GEOD-22880 | biostudies-arrayexpress
TranscriptomicsThe effects of Hmgb1 depletion on gene expression in human cells
High Mobility Group Box 1 (HMGB1) is a highly abundant and evolutionarily conserved non-histone chromatin component with the ability to bind and bend DNA. The protein is involved in fundamental nuclear processes including nucleosome sliding, transcription, replication, V(D)J recombination and DNA tr...
ORGANISM(S): Homo sapiens 
2011-06-28 | E-GEOD-18721 | biostudies-arrayexpress
TranscriptomicsThe effects of Hmgb1 depletion on gene expression in murine cells
High Mobility Group Box 1 (HMGB1) is a highly abundant and evolutionarily conserved non-histone chromatin component with the ability to bind and bend DNA. The protein is involved in fundamental nuclear processes including nucleosome sliding, transcription, replication, V(D)J recombination and DNA tr...
ORGANISM(S): Mus musculus 
2013-10-01 | E-GEOD-18463 | biostudies-arrayexpress
TranscriptomicsThe epigenetic landscape of human colorectal cancer
We characterized the epigenetic landscape of human colorectal cancer (CRC). To this extent, we performed gene expression profiling using high throughput sequencing (RNA-seq) and genome wide binding/occupancy profiling (ChIP-seq) for histone modifications correlated to transcriptional activity, enhan...
ORGANISM(S): Homo sapiens 
2021-02-23 | E-MTAB-8416 | biostudies-arrayexpress
TranscriptomicsThe epigenetic landscape of human colorectal cancer
We characterized the epigenetic landscape of human colorectal cancer (CRC). To this extent, we performed gene expression profiling using high throughput sequencing (RNA-seq) and genome wide binding/occupancy profiling (ChIP-seq) for histone modifications correlated to transcriptional activity, enhan...
ORGANISM(S): Homo sapiens 
2021-03-10 | E-MTAB-8448 | biostudies-arrayexpress
TranscriptomicsExpression profiling of nhp6 mutants and wildtype yeast cells (Saccharomyces cerevisiae)
The basic unit of genome packaging is the nucleosome, and nucleosomes have long been proposed to restrict DNA accessibility both to damage and to transcription. However, nucleosome number in cells was considered fixed, and no condition was described where nucleosome number was reduced. We show here ...
ORGANISM(S): Saccharomyces cerevisiae 
2011-05-19 | E-GEOD-23711 | biostudies-arrayexpress
UnknownEpigenetic regulation by Polycomb Repressive Complex 1 promotes Cerebral Cavernous Malformations
Not available
S-SCDT-10_1038-S44321-024-00152-9 | biostudies-other
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