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During seed imbibition, lipids are engaged in membrane reorganization while facing free radical-mediated oxidative injury. In the present work, we explored changes in lipid components at different timepoints of imbibition (0.5, 2, 4, 6, and 8 h) in the legume Medicago truncatula, by combining bio...

2019-10-14 | MTBLS181 | MetaboLights
For 13 patients with JAK2 exon 12-mutated polycythemia vera (PV), we compared genome-wide RNA profiles of JAK2-mutant (mutant) and wild-type erythroid colonies, grown from a single patient in the same culture plate. This paired approach controls for factors including age, gender, treatment, germline...
ORGANISM(S): Homo sapiens 
E47 is a basic Helix Loop Helix (bHLH) transcription factor that has important roles in cell fate determination and differentiation of many cell types. In the nervous system E47 heterodimerizes with tissue-specific, pro-neural bHLH transcription factors and activates downstream target genes. To iden...
ORGANISM(S): Homo sapiens 
Molecular profiling of blastic plasmacytoid dendritic cell neoplasm reveals a unique pattern and suggests selective sensitivity to nf-kb pathway inhibition To better understand the pathobiology of BPDCN and discover new targets for effective therapies, the gene expression profile (GEP) of 25 BPDCN s...
ORGANISM(S): Homo sapiens 
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