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TranscriptomicsUnderstanding transcriptional changes associated with the transition to selfing in Arabidopsis thaliana
RNA-seq reads from the selfing species Arabidopsis thaliana were produced from flowers to study the consequences of the transition from the ancestral state (outcrossing) to the derived state (selfing). This was done in the context of examining another species in the Arabidopsis genus (A. lyrata) and...
ORGANISM(S): Arabidopsis thaliana 
2013-04-02 | E-GEOD-45685 | biostudies-arrayexpress
ProteomicsMebendazole Inhibits Histoplasma capsulatum In Vitro Growth and Decreases Mitochondrion and Cytoskeleton Protein Levels
Histoplasmosis is a frequent mycosis in people living with HIV/AIDS and other immunocompromised hosts. Histoplasmosis has high rates of mortality in these patients if treatment is unsuccessful. Itraconazole and amphotericin B are used to treat histoplasmosis; however, both antifungals have potential...
ORGANISM(S): Fungi Histoplasma capsulatum 
2023-03-22 | PXD033762 | Pride
Histoplasma capsulatum  mebendazole  drug repositioning. antifungal activity Proteomic analysis 
GenomicsDNA Methylation by Reduced Representation Bisulfite Seq from ENCODE/HudsonAlpha
This data was generated by ENCODE. If you have questions about the data, contact the submitting laboratory directly (Florencia Pauli mailto:fpauli@hudsonalpha.org). If you have questions about the Genome Browser track associated with this data, contact ENCODE (mailto:genome@soe.ucsc.edu). This trac...
ORGANISM(S): Homo sapiens 
2011-03-01 | E-GEOD-27584 | biostudies-arrayexpress
TranscriptomicsSystematic evaluation of variability in simulated ChIP-chip experiments
The most widely-used method for detecting and measuring genome-wide protein-DNA interactions is chromatin immunoprecipitation on tiling microarrays, commonly known as ChIP-chip. Many tiling array platforms, amplification methods, and analysis algorithms exist for ChIP-chip, but a rigorous assessment...
ORGANISM(S): Homo sapiens 
2008-01-31 | E-GEOD-9842 | biostudies-arrayexpress
ProteomicsProteomics reveals virulence-related proteins in Paracoccidioides brasiliensis and Paracoccidioides lutzii yeast cells grown in the presence of L-dihydroxyphenylalanine
Species of the genus Paracoccidioides cause a systemic infection in human patients. Yeast cells of Paracoccidioides spp. produce melanin in the presence of L-dihydroxyphenylalanine and during infection, which may impact the pathogen survival into the host. To better understand the metabolic changes ...
ORGANISM(S): Fungi Paracoccidioides brasiliensis (strain Pb18) Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides brasiliensis) 
2021-01-20 | PXD021711 | Pride
L-dihydroxyphenylalanine Proteomics Virulence Melanin Paracoccidioides 
UnknownUse of quantitative molecular diagnostic methods to assess the aetiology, burden, and clinical characteristics of diarrhoea in children in low-resource settings: a reanalysis of the MAL-ED cohort study.
Not available
S-EPMC6227251 | biostudies-literature
UnknownPredicting 90-day survival of patients with COVID-19: Survival of Severely Ill COVID (SOSIC) scores.
Not available
S-EPMC8665857 | biostudies-literature
UnknownLimitation of life-sustaining therapies in critically ill patients with COVID-19: a descriptive epidemiological investigation from the COVID-ICU study.
Not available
S-EPMC10006561 | biostudies-literature
UnknownPEEP-AKI-COVID ICU: Effect of positive end-expiratory pressure on acute kidney injury development in patients with COVID-19-associated acute respiratory distress syndrome: an ancillary analysis of the COVID-ICU study.
Not available
S-EPMC12574259 | biostudies-literature
UnknownCharacteristics and prognosis of bloodstream infection in patients with COVID-19 admitted in the ICU: an ancillary study of the COVID-ICU study.
Not available
S-EPMC8708508 | biostudies-literature
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