Paige A L AL - OmicsDI

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Unknown (2)
Proteomics (2)
Genomics (1)
Transcriptomics (1)
Metabolomics (1)

Organisms

Homo sapiens (2)
Mus musculus (1)

Repository

biostudies-arrayexpress (2)
MassIVE (1)
MetaboLights (1)
pride (1)

Tissue

Bone marrow (1)
Myeloid cell (1)

Disease

Acute leukemia (1)

Technology Type

Mass spectrometry (1)
Bottom-up proteomics (1)
Mass Spectrometry (1)

Instrument Platform

Exactive Plus (1)
Flow injection analysis MS - negative (1)
Flow injection analysis MS - positive (1)

Publication Date

2016 (1)
2013 (1)
2020 (1)
2023 (1)
2025 (1)

CHEBI ID

CHEBI:10072 (1)
CHEBI:1148 (1)
CHEBI:11814 (1)
CHEBI:12936 (1)
CHEBI:12962 (1)
CHEBI:133083 (1)
CHEBI:1387 (1)
CHEBI:14314 (1)
CHEBI:144330 (1)
CHEBI:15318 (1)
CHEBI:15344 (1)
CHEBI:15346 (1)
CHEBI:15351 (1)
CHEBI:15354 (1)
CHEBI:15355 (1)
CHEBI:15380 (1)
CHEBI:15414 (1)
CHEBI:15422 (1)
CHEBI:15468 (1)
CHEBI:1547 (1)
CHEBI:15473 (1)
CHEBI:15487 (1)
CHEBI:15517 (1)
CHEBI:15531 (1)
CHEBI:15533 (1)
CHEBI:15539 (1)
CHEBI:15551 (1)
CHEBI:15552 (1)
CHEBI:15555 (1)
CHEBI:15584 (1)

Metabolite Name

(4R)-4-Hydroxy-L-glutamic acid (1)
(R)-3-Hydroxybutyric acid (1)
(S)-3-Hydroxybutyric acid (1)
1,3-Diaminopropane (1)
1-Methyl-L-histidine (1)
1-Methylhistamine (1)
1-Methylnicotinamide (1)
2,3-Dihydroxypropanoic acid (1)
2,3-Dihydroxypropyl hexopyranoside (1)
2,3-Diphospho-D-glyceric acid (1)
2,3-Pyridinedicarboxylic acid (1)
2,5-Dihydroxybenzaldehyde (1)
2,5-Dihydroxybenzoic acid (1)
2-(Hydroxymethyl)butanoic acid (1)
2-Amino-3-methoxybenzoic acid (1)
2-Aminoadipic acid (1)
2-Deoxy-5-cytidylic acid (1)
2-Deoxy-D-ribonic acid (1)
2-Deoxy-D-ribose (1)
2-Deoxyadenosine (1)
2-Deoxyadenosine 5-triphosphate (1)
2-Deoxycytidine (1)
2-Deoxycytidine 5-diphosphate (1)
2-Deoxyguanosine (1)
2-Deoxyguanosine 5-diphosphate (1)
2-Deoxyguanosine 5-triphosphate (1)
2-Deoxyinosine (1)
2-Deoxyribose-5-phosphate (1)
2-Deoxyuridine (1)
2-Deoxyuridine 5-monophosphate (1)

Study type

ChIP-seq (1)
Transcription profiling by array (1)

Release Date

2016 (1)
2013 (1)
2024 (1)
2018 (1)

Lab affiliation

Chemistry Department, The Scripps Research Institute, La Jolla, California, USA (1)

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TMEM88 knockdown during human embryonic stem cell cardiac differentiation

TMEM88 is indispensable for heart development and acts in the pre-cardiac mesoderm to specify lineage commitment of the cardiovascular progenitor cell through inhibition of Wnt signaling. 2 different lentiviruses expression shRNA targeting different domains of the TMEM88 locus were transduced into u...

ORGANISM(S): Homo sapiens

2013-10-21 | E-GEOD-43805 | biostudies-arrayexpress

Genome-wide chromatin binding of Elk1 and Gli2 in chemical induced neural reprogramming

Cellular reprogramming using chemically defined conditions, without genetic manipulation, is a promising approach for generating clinically relevant cell types for regenerative medicine and drug discovery. However, small molecule-driven approaches for inducing lineage-specific stem cells from somati...

ORGANISM(S): Mus musculus

2016-05-15 | E-GEOD-78976 | biostudies-arrayexpress

Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase

Metabolic networks are interconnected and influence diverse cellular processes. The protein-metabolite interactions that mediate these networks are frequently low affinity and challenging to systematically discover. We developed mass spectrometry integrated with equilibrium dialysis for the disco...

2023-08-07 | MTBLS7237 | MetaboLights

3x-HA Tagged PAF1 IP-Ms in MOLM-13 CAS9 cells

Transcriptional regulatory proteins are frequent drivers of oncogenesis and common targets for drug discovery. The transcriptional co-activator, ENL, which binds to chromatin through an acetyllysine reader YEATS domain, is preferentially required for the survival and pathogenesis of acute leukemia. ...

ORGANISM(S): Homo sapiens (Human)

2025-10-21 | PXD066867 | Pride

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Purposing

An outbreak of the novel coronavirus SARS-CoV-2, the causative agent of COVID-19 respiratory disease, has infected over 170,000 people since the end of 2019, killed over 7,400, and caused worldwide social and economic disruption. SARS-CoV-2 infection has a mortality rate of 3.4% among confirmed case...

ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2 (ncbitaxon:2697049) Homo Sapiens (ncbitaxon:9606)

2020-03-24 | MSV000085144 | MassIVE

AI is a viable alternative to high throughput screening: a 318-target study.

Not available

S-EPMC10987645 | biostudies-literature

Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies.