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TranscriptomicsNovartis 12 Strain Diet Sex Survey
High-fat diets are associated with increased obesity and metabolic disease in mice and humans. Here we used analysis of variance (ANOVA) to scrutinize a microarray data set consisting of 10 inbred strains of mice from both sexes fed atherogenic high-fat and control chow diets. An overall F-test was ...
ORGANISM(S): Mus musculus 
2008-12-10 | E-GEOD-10493 | biostudies-arrayexpress
TranscriptomicsMRLxSM eQTL in Liver by RMA on Ensembl transcripts
A QTL analysis between inbred mouse strains MRL/MpJ and SM/J was performed to identify genetic loci influencing high-density lipoprotein (HDL) cholesterol and triglycerides (TG) at eight weeks of age in F2 mice fed a chow diet. In order to narrow down lists of candidate genes, expression levels from...
ORGANISM(S): Mus musculus 
2011-11-28 | E-GEOD-25322 | biostudies-arrayexpress
TranscriptomicsGene expression comparison of liver tissue from C57BL/6J and KK/HIJ mice
A QTL intercross was performed bewteen C57BL/6J and KK/HIL for albuminurea, asthma and cardiovascular related phenotypes. Several QTL were identified for most phenotypes. We performed microarray analysis from liver samples to identify genes differentially expressed between the parental strains. The ...
ORGANISM(S): Mus musculus 
2012-10-18 | E-GEOD-37429 | biostudies-arrayexpress
TranscriptomicsUncovering Genes and Regulatory Pathways Related to Urinary Albumin Excretion in Mice
Identifying the genes underlying quantitative trait loci (QTL) for disease has proven difficult, mainly due to the low resolution of the approach and the complex genetics involved. However, recent advances in bioinformatics and the availability of genetic resources now make it possible to narrow the...
ORGANISM(S): Mus musculus 
2011-02-01 | E-GEOD-23310 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of livers from mice overexpress ABCA1 in LDL receptor -/- genetic background to characterize the effects of ABCA1 overexpression.
Changes in the transcript profile due to ABCA1 expression in murine liver samples was evaluated in LDL receptor -/- genetic backgrounds. Experiment Overall Design: Case (ABCA1-transgenic) versus control (wild-type) design with 4 biological replicates per condition
ORGANISM(S): Mus musculus 
2007-11-13 | E-GEOD-5496 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of hypertension disease induced by treating mice with salt water (vs plain water as control) RNA collected from 5 tissues (Brain stem, Brain, liver, kidney, and heart) of two strains (SWR and C3H)
Gene expression profiling of hypertension disease induced by treating mice with salt water (vs. plain water as control). RNA are collected from 5 tissues (Brain stem, Brain, liver, kidney, and heart) of two strains (SWR and C3H)
ORGANISM(S): Mus musculus 
2005-01-01 | E-TIGR-87 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of hypertension disease induced by treating mice with salt water (vs plain water as control) RNA collected from 5 tissues (Brain stem, Brain, liver, kidney, and heart) of two strains (SWR and C3H)
Gene expression profiling of hypertension disease induced by treating mice with salt water (vs. plain water as control). RNA are collected from 5 tissues (Brain stem, Brain, liver, kidney, and heart) of two strains (SWR and C3H)
ORGANISM(S): Mus musculus 
2005-01-01 | E-TIGR-88 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of hypertension disease induced by treating mice with salt water (vs plain water as control) RNA collected from 5 tissues (Brain stem, Brain, liver, kidney, and heart) of two strains (SWR and C3H)
Gene expression profiling of hypertension disease induced by treating mice with salt water (vs. plain water as control). RNA are collected from 5 tissues (Brain stem, Brain, liver, kidney, and heart) of two strains (SWR and C3H)
ORGANISM(S): Mus musculus 
2005-01-01 | E-TIGR-89 | biostudies-arrayexpress
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