Comparison of gene expression in macrophages from ulcerative colitis patients or healthy control individuals, either unstimulated or stimulated with heat killed E. coli
We conducted whole-genome sequencing of probands from several melanoma families, identifying one individual carrying a novel germline variant (c.G1075A, NM_000248.3; p.E318K, NP_000239.1; rs149617956) in the melanoma lineage-specific oncogene MITF. While the variant cosegregated with melanoma in ...
