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Crohn's disease (CD) is a debilitating inflammatory bowel disease (IBD), that, like all complex disorders, emerges on a background of many genetic and environmental factors. miRNAs can play an important role in the induction of autoimmune diseases and IBD. The aim of our study was to identify, besid...
ORGANISM(S): Homo sapiens 
We mapped the genome-wide binding of C-terminally FLAG-tagged AraC in S. enterica subsp. enterica serovar Typhimurium strain 14028s using ChIP coupled with deep sequencing (ChIP-seq). We identified five putative target loci for AraC: upstream of araB/araC, araE, araJ, STM14_0178, and within sseD.
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S 
Streptomyces coelicolor is a model organism for the study of Streptomyces, a genus of Gram-positive bacteria that undergoes a complex life cycle and produces an enormous repertoire of bioactive metabolites and extracellular enzymes. This study investigated the production and characterization of memb...
ORGANISM(S): Streptomyces coelicolor A3(2) 
2021-11-02 | PXD024085 | Pride
We used RNA-seq to determine the effects of AraC and arabinose on RNA levels genome-wide in S. enterica. Wild-type or delta araC mutant cells were grown in both the presence and absence of 0.2% L-arabinose. RNA-Seq libraries from two independent biological replicate samples were sequenced for (i) wi...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. 14028s Wu 
Yeast lacking the H3 or H4 amino termini, and corresponding wild type strains, were grown in synthetic media. These conditions induce Gcn4-activated transcription. Experiment Overall Design: Three replicates of the H4del(2-26) and corresponding wild type strains, and four replicates of the H3del(1-...
ORGANISM(S): Saccharomyces cerevisiae 
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