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TranscriptomicsH. pylori genotypes and host gene expression profiles
H. pylori virulence factors have been suggested to be important in determining the outcome of infection. The H. pylori adhesion protein BabA2 is thought to play an crucial role in bacterial colonization and in induction of a severe gastric inflammation, particularly in combination with expression of...
ORGANISM(S): Homo sapiens 
2008-05-01 | E-GEOD-6143 | biostudies-arrayexpress
TranscriptomicsGene expression changes induced by the pan-PIM inhibitor ETP-39010 in 4 peripheral T cell lymphoma cell lines
Peripheral T cell lymphoma (PTCL) is a very aggressive disease which currently lacks efficient targeted therapy. New therapeutic strategies are needed to improve the very poor outcome of these patients. In these study we hypothesized that PIM kinases could be of therapeutic value in PTCL because we ...
ORGANISM(S): Homo sapiens 
2014-11-14 | E-GEOD-42595 | biostudies-arrayexpress
TranscriptomicsH. salinarum NRC-1 vs VNG2099C knockout
To investigate the contribution of ribonucleases to post-transcriptional regulation of mRNA levels, we examined the fitness consequences and gene expression changes of ribonuclease mutants in the extreme halophilic archaeon Halobacterium salinarum NRC-1. H. salinarum NRC-1 is known to use a large re...
ORGANISM(S): Halobacterium sp. NRC-1 
2014-03-03 | E-GEOD-45988 | biostudies-arrayexpress
TranscriptomicsThe pan-genome of the dominant human gut-associated archaeon, Methanobrevibacter smithii
The human gut microbiota harbors methanogens represented by the dominant archaeon, Methanobrevibacter smithii, a polyphyletic group of acetogens, and sulfate-reducing bacteria. Defining their roles in the H2-economy of the gut has potential therapeutic importance for modulating the efficiency of fe...
ORGANISM(S): Methanobrevibacter smithii 
2011-03-30 | E-GEOD-25408 | biostudies-arrayexpress
TranscriptomicsProbing the pan genome of a foodborne bacterial pathogen Listeria monocytogenes
Full title: Probing the pan genome of a foodborne bacterial pathogen Listeria monocytogenes: Implications for its niche adaptation, pathogenesis, and evolution Listeria monocytogenes is a foodborne bacterial pathogen well known for adaptability to diverse environmental and host niches, and a high f...
ORGANISM(S): Listeria monocytogenes EGD-e 
2010-04-06 | E-GEOD-20367 | biostudies-arrayexpress
TranscriptomicsH. salinarum transcriptome dynamics in response to 0.85mM extracellular copper
Halobacterium salinarum is a halophillic archea that is capable of sustaining growth despite dramatic changes to the concentration of ions in its extracellular environment. Here we studied H. salinarum's specific adaptation response to the transition metal copper. Analysis utilized pre-treatment (t...
ORGANISM(S): Halobacterium sp. NRC-1 
2012-06-29 | E-GEOD-39028 | biostudies-arrayexpress
TranscriptomicsMethanobrevibacter smithii expression profiling
This SuperSeries is composed of the following subset Series: GSE25408: The pan-genome of the dominant human gut-associated archaeon, Methanobrevibacter smithii GSE25535: Expression data from an in vitro growth of Methanobrevibacter smithii PS Refer to individual Series
ORGANISM(S): Methanobrevibacter smithii ATCC 35061 
2011-11-07 | E-GEOD-25537 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of liver from Pan troglodytes with chronic hepatitis C virus infection following therapeutic silencing of microRNA-122 using SPC3649
Chimpanzees with chronic Hepatitis C infection treated with LNA-antimiR-122.
ORGANISM(S): Pan troglodytes 
2010-10-01 | E-MEXP-2375 | biostudies-arrayexpress
GenomicsPlasmodium knowlesi strain H
RNA-seq of Plasmodium knowlesi
PRJDB12907 | ENA
TranscriptomicsRNA-seq of tumor-educated platelets enables blood-based pan-cancer, multiclass and molecular pathway cancer diagnostics
We report RNA-sequencing data of 283 blood platelet samples, including 228 tumor-educated platelet (TEP) samples collected from patients with six different malignant tumors (non-small cell lung cancer, colorectal cancer, pancreatic cancer, glioblastoma, breast cancer and hepatobiliary carcinomas). I...
ORGANISM(S): Homo sapiens 
2015-10-30 | E-GEOD-68086 | biostudies-arrayexpress
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