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TranscriptomicsSingle-nucleus RNA-seq of adult chimpanzee and bonobo livers
Single-nucleus RNA-seq was performed on the liver samples from adult chimpanzees and bonobos. Two individuals were included for both species. The single-nucleus libraries were generated using the 10X Chromium Next GEM Single Cell 3ʹ platform and sequenced on Illumina NextSeq 550. This dataset is par...
ORGANISM(S): Pan paniscus 
2026-07-13 | E-MTAB-15548 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of FNR transcriptional regulator and NarP response regulator knock-out strains of Neisseria gonorrhoeae
Knock out mutants of FNR transcriptional regulator (NGO1579) and NarP response regulator (NGO0752) in N. gonorrhoeae compared to parent strain grown in liquid culture.
ORGANISM(S): Neisseria gonorrhoeae 
2006-08-15 | E-MEXP-726 | biostudies-arrayexpress
TranscriptomicsComparison of gene expression data between wild-type and DM1-affected cells
This SuperSeries is composed of the following subset Series: GSE7177: Comparison of gene expression data between wild-type and DM1-affected Mesodermal Precursors Cells (MPC) GSE7178: Comparison of gene expression data between wild-type and DM1-affected Neural Precursors Cells (NPC) GSE7179: Comparis...
ORGANISM(S): Homo sapiens 
2010-03-09 | E-GEOD-7214 | biostudies-arrayexpress
GenomicsGenome-wide location analysis of WNT (Tcf7l2) and BMP (SMAD1) in human hematopoeitic progenitors co-occupied with lineage specific regulators (GATA1, GATA2)
Lineage regulators direct BMP and Wnt pathways to cell-specific programs during differentiation and regeneration. This represents the human CD34 ChIP-seq portion of this dataset. Human hematopoietic cells were cross-linked with formaldehyde for 20 min. DNA was enriched by chromatin immunoprecipitati...
ORGANISM(S): Homo sapiens 
2011-10-07 | E-GEOD-29194 | biostudies-arrayexpress
GenomicsGenome-wide location analysis of WNT (Tcf7l2) and BMP (SMAD1) in human hematopoeitic cell lines co-occupied with lineage specific regulators (GATA1, GATA2, CEBPA)
Lineage regulators direct BMP and Wnt pathways to cell-specific programs during differentiation and regeneration. This represents the human ChIP-seq portion of this dataset on leukemia cell lines. Human hematopoietic cells were cross-linked with formaldehyde for 20 min. DNA was enriched by chromatin...
ORGANISM(S): Homo sapiens 
2011-10-07 | E-GEOD-29195 | biostudies-arrayexpress
GenomicsGenome-wide location analysis of BMP (SMAD1) in mouse erythroid progenitors co-occupted with lineage specific regulators (GATA1, GATA2)
Lineage regulators direct BMP and Wnt pathways to cell-specific programs during differentiation and regeneration Mouse G1E or G1ER cells were cross-linked with formaldehyde for 20 min. DNA was enriched by chromatin immunoprecipitation (ChIP) and analyzed by Solexa sequencing. A sample of whole cell...
ORGANISM(S): Mus musculus 
2011-10-07 | E-GEOD-29193 | biostudies-arrayexpress
TranscriptomicsMulti-omics analysis of human bone marrow across fetal and adult stages informs strategies for in vitro B lymphopoiesis - scRNA-seq dataset
These samples are part of a study aimed at understanding B lymphopoiesis in the human bone marrow throughout the lifespan and guiding in vitro B lymphopoiesis. This dataset contains transcriptomic data from prenatal and adult bone marrow samples, as well as in vitro experiments, together with the co...
ORGANISM(S): Homo sapiens 
2026-09-11 | E-MTAB-17252 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA and B cell receptor profiling of B cell response to SARS-CoV-2 vaccination
We generated single-cell transcriptomic and BCR sequencing data of B cells from peripheral blood samples taken from a SARS-CoV-2-antigen-naive cohort being vaccinated with the SARS-CoV-2 mRNA-1273 vaccine. Blood samples were collected at the baseline timepoint D-1 (i.e. one day prior to the initial ...
ORGANISM(S): Homo sapiens 
2026-05-08 | E-MTAB-16531 | biostudies-arrayexpress
GenomicsCell-free DNA comprises an in vivo, genome-wide nucleosome footprint that informs its tissue(s)-of-origin
Nucleosomes are the basic unit of packaging of eukaryotic chromatin, and nucleosome positioning can differ substantially between cell types. Here, we sequence 14.5 billion plasma-borne cell-free DNA (cfDNA) fragments (700-fold coverage) to generate genome-wide maps of in vivo nucleosome occupancy. W...
ORGANISM(S): Homo sapiens 
2015-11-04 | E-GEOD-71378 | biostudies-arrayexpress
TranscriptomicsMulti-omics analysis of human bone marrow across fetal and adult stages informs strategies for in vitro B lymphopoiesis - scBCR-seq dataset
These samples are part of a study aimed at understanding B lymphopoiesis in the human bone marrow throughout the lifespan and guiding in vitro B lymphopoiesis. This dataset contains B cell receptor data from prenatal and adult bone marrow samples, as well as in vitro experiments, together with the c...
ORGANISM(S): Homo sapiens 
2026-09-09 | E-MTAB-17239 | biostudies-arrayexpress
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