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Proteomicsthe Effect of Fatty Acids in Hepatic Insulin resistance-part2
Monounsaturated fatty acid (MUFA) oleic acid (OA) has been reported to reverse saturated fatty acid palmitic acid (PA)-induced hepatic insulin resistance (IR). However, the detailed molecular mechanism remains elusive. In addition, previous research also showed that -3 polyunsaturated fatty acid (PU...
ORGANISM(S): Homo sapiens (Human) 
2019-07-11 | PXD012066 | Pride
Human  free fatty acids  insulin resistance  quantitative proteomics  calcium  atp. 
TranscriptomicsExpression data from mouse T cells after CLIP (Crosslinking immunoprecipitation) procedures (mRNA)
Molecular networks based on genome-wide mRNA and miRNA expression in activated T cells are interated by co-regulation with miRNA and protein-coding genes during immune responses, however, accurate prediction of miRs and their targets remains a challenge. Furthermore, the specific changes in the expr...
ORGANISM(S): Mus musculus 
2013-01-19 | E-GEOD-43635 | biostudies-arrayexpress
TranscriptomicsIdentifying genes dysregulated in patients with acute myocardial infarction
Twenty-three AMI patients and 23 non-AMI healthy controls were included in this pilot study. Tissue samples were cut at 10 μm from formalin fixed paraffin-embedded tissue blocks using a microtome. Six to eight 10-μm sections were used for the isolation procedure. Total RNA isolation was performed us...
ORGANISM(S): Homo sapiens 
2016-05-11 | E-MTAB-3573 | biostudies-arrayexpress
TranscriptomicsExpression data from mouse T cells after CLIP (Crosslinking immunoprecipitation) procedures
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2013-01-19 | E-GEOD-43636 | biostudies-arrayexpress
GenomicsGenome-wide mapping of nucleosome positioning and DNA methylation within Individual DNA molecules
DNA methylation and nucleosome positioning work together to generate chromatin structures that regulate gene expression. Nucleosomes are typically mapped using nuclease digestion requiring significant amounts of material and varying enzyme concentrations. We have developed a method (NOMe-seq) that u...
ORGANISM(S): Homo sapiens 
2012-09-12 | E-GEOD-40770 | biostudies-arrayexpress
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