Pancreatic islets

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Unknown (2838)
Transcriptomics (1161)
Genomics (1082)
Proteomics (123)
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Metabolomics (11)

Organisms

Mus musculus (649)
Homo sapiens (609)
Rattus norvegicus (99)
Bartonella quintana JK 31 (95)
Bombyx mori (95)
Onchocerca volvulus (95)
Klebsiella pneumoniae (95)
Musca domestica (95)
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Sus scrofa (4)
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mouse gut metagenome (3)
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Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S (1)
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synthetic construct (1)

Organisms

Mus musculus (484)
Homo sapiens (239)
Rattus norvegicus (58)
Danio rerio (7)
Mus musculus musculus (2)
Macaca mulatta (2)
Ovis aries (2)
Sus scrofa (2)
mouse gut metagenome (2)
Rattus (1)
Mus sp. (1)
Mus (1)
Canis lupus familiaris (1)
Mus musculus domesticus (1)
unidentified (1)

Repository

ENA (891)
biostudies-arrayexpress (659)
geo (643)
pride (95)
EGA (58)
MassIVE (17)
ExpressionAtlas (13)
BioModels (11)
jPOST (5)
MetaboLights (5)
MetabolomicsWorkbench (4)
iProX (3)
GNPS (2)
NODE (2)
PanoramaPublic (2)
EVA (1)
GPMDB (1)
PMR (1)

Tissue

Pancreatic islet (28)
Cell culture (20)
Pancreas (19)
Islet of Langerhans (19)
Pancreatic islet cell (11)
Type B pancreatic cell (5)
Pancreatic islet beta cell (4)
Epithelial cell (4)
Pancreas (3)
Endocrine pancreas (3)
B cell (3)
Beta-TC3 cell (2)
Alpha-TC1.6 cell (2)
Pancreatic alpha cell (2)
Adipose tissue (2)
Bone marrow (2)
Macrophage (2)
Blood plasma (2)
Stem cell (2)
Fibroblast (2)
Primary cell (2)
Permanent cell line cell (2)
Liver (2)
Cultured cells (1)
Pancreatic islets (1)
Pancreatic islet (1)
Cellular modified amino acid catabolic process (1)
Pancreatic islet cancer cell (1)
Insulin secreting cell (1)
Secretory granule (1)

Disease

Type 2 diabetes mellitus (16)
Type 1 diabetes mellitus (14)
Disease free (6)
Normal (5)
Diabetes mellitus (2)
Pancreatic ductal adenocarcinoma (2)
Diabetes (2)
4T1 tumor-bearing (1)
Aggressive insulitis (1)
Nondiabetic (1)
Perineural invasion (1)
Mild hyperglycemia (1)
Mild hyperglycemia, liver dysfunction, and renal glycosuria (1)
Chronic pancreatitis (1)
Pancreatic cancer (1)
Pancreatic adenocarcinoma (1)
Normal (1)
No disease (1)
Healthy donor tissue (1)
Adenocarcinoma (1)
Not Available (1)
Maturity-onset diabetes of the young type 1 (1)
Obesity (1)
Diabetes mellitus (1)
Insulinoma (1)
Pancreatic endocrine carcinoma (1)
Cystic fibrosis (1)

Technology Type

Mass Spectrometry (99)
Shotgun proteomics (45)
Bottom-up proteomics (21)
Data-independent acquisition (12)
Affinity purification coupled with mass spectrometry proteomics (11)
Data-dependent acquisition (10)
Top-down proteomics (9)
Mass spectrometry assay (4)
ILLUMINA, Illumina HiSeq 2500 (2)
Illumina HiSeq 2000 (2)
EI (2)
ESI (2)
All-ion fragmentation (2)
SRM/MRM (2)
ILLUMINA, Illumina Genome Analyzer IIx, Illumina HiSeq 2500 (1)
Mass spectrometry (1)
DiaPASEF (1)
SWATH MS (1)

Instrument Platform

Illumina HiSeq 2000 (21)
Illumina HiSeq 2500 (19)
Illumina HiSeq 4000 (17)
Illumina NovaSeq 6000 (16)
NextSeq 500 (14)
Affymetrix Fluidics Station 400 (6)
Affymetrix GeneChip Scanner 3000 (GCS3000) (3)
G2500A Hewlett Packard (3)
Illumina Genome Analyzer IIx (3)
NextSeq 2000 (3)
Agilent DNA Microarray Scanner Model #G2565BA (2)
Illumina Genome Analyzer II (2)
Illumina HiSeq 1000 (2)
Illumina MiSeq (2)
Illumina HiSeq 3000 (2)
NuGEN Trio low input RNA-seq (1)
RNeasy Micro Kit (QIAGEN #74004) (1)
PALM Microbeam Rel. 4.9 with RoboMover microscope (Zeiss) (1)
All computation performed on the Vanderbilt ACCRE cluster. (1)
Qiagen MinElute (1)
Affymetrix GeneArray Scanner (1)
Affymetrix GeneChip Scanner 3000 7G (1)
Illumina Genome Analyzer (1)
GenePix 4000A [Axon Instruments] (1)
NanoDrop (1)
Scanning hardware (1)
Illumina (1)
GenePix 4000B (1)
DNBSEQ-G400 (1)
ACCRE (1)

Publication Date

2014 (131)
2023 (118)
2024 (96)
2022 (94)
2013 (94)
2021 (92)
2015 (92)
2025 (84)
2016 (78)
2012 (77)
2026 (72)
2010 (64)
2020 (59)
2019 (55)
2011 (47)
2018 (43)
2017 (38)
2008 (37)
2009 (33)
2007 (22)
2006 (13)
2005 (10)
2003 (2)
2004 (1)

UNIPROT ID/AC

Q9NQ88 (1)
Q9UJ73 (1)
Q9UMQ9 (1)
Q9UMR0 (1)
Q01813 (1)
P14618 (1)
P17858 (1)
P35557 (1)
O60825 (1)
Q16875 (1)
P16118 (1)
Q16877 (1)
P05062 (1)
P09972 (1)
P04075 (1)
P07738 (1)
P00338 (1)
P07195 (1)
Q9BYZ2 (1)
P07864 (1)
P04406 (1)
P01308 (1)
P30613 (1)
P06744 (1)
P06733 (1)
P09104 (1)
P13929 (1)
O00757 (1)
P09467 (1)
P08237 (1)

CHEBI ID

CHEBI:16761 (4)
CHEBI:29108 (3)
CHEBI:14314 (3)
CHEBI:16905 (2)
CHEBI:15422 (2)
CHEBI:16908 (2)
CHEBI:80332 (1)
CHEBI:145810 (1)
CHEBI:20933 (1)
CHEBI:12351 (1)
CHEBI:42586 (1)
CHEBI:4122 (1)
CHEBI:11065 (1)
CHEBI:18783 (1)
CHEBI:12411 (1)
CHEBI:12965 (1)
CHEBI:20999 (1)
CHEBI:58579 (1)
CHEBI:16651 (1)
CHEBI:8685 (1)
CHEBI:26462 (1)
CHEBI:26466 (1)
CHEBI:45253 (1)
CHEBI:14987 (1)
CHEBI:26054 (1)
CHEBI:44894 (1)
CHEBI:58702 (1)
CHEBI:14812 (1)
CHEBI:26055 (1)
CHEBI:8147 (1)

Metabolite Name

D-glucopyranuronic acid (1)
(Z)-icos-11-enoic acid (1)
D-fructofuranose 6-phosphate (1)
Cellotriose (1)
Aldehydo-L-arabinose (1)
Beta-lactose (1)
Aldehydo-D-ribose 5-phosphate (1)
D-glucopyranose 6-phosphate (1)
N(pros)-methyl-L-histidine (1)
L-alpha-aminobutyric acid (1)
L-rhamnopyranose (1)
1,5-anhydro-D-glucitol (1)
Glycylglycine (1)
All-cis-docosa-4,7,10,13,16,19-hexaenoic acid (1)
Maltitol (1)
¦Ã-Glu-Lys (1)
Cyclo(leu-phe) (1)
Alpha-Asarone (1)
[(2R)-3-Hexadecoxy-2-hydroperoxypropyl] 2-(trimethylazaniumyl)ethyl phosphate (1)
Trp-Ala-Asp (1)
Triphenyl-phosphate (1)
Trimethylamine-N-Oxide (1)
Triethyl-phosphate (1)
Thr-Val-Leu (1)
Thiamine-Monophosphate (1)
Tetraethylene-glycol (1)
Shinorine (1)
Ser-Phe-Ala (1)
ST-638 (1)
SPH(d18:2) (1)

First Public Date

2023 (112)
2024 (111)
2025 (89)
2014 (89)
2021 (78)
2022 (75)
2026 (74)
2020 (64)
2019 (49)
2017 (41)
2018 (36)
2015 (32)
2016 (25)
2013 (14)
2012 (1)
2010 (1)

Modelling Approach

Ordinary differential equation model (9)
Agent-based model (1)
Differential equation model (1)

Lab affiliation

Kubicek lab, Principal Investigator, Head of Molecular Discovery Platform, CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria (3)
Department of Fundamental Neurosciences, Rue du Bugnon 9, 1005, Lausanne (3)
Department of Clinical Science, Faculty of Medicine, University of Bergen, Norway (3)
Department of Clinical Science, University of Bergen, Norway (2)
Proteomics and Metabolomics Core Facility, Biomedical Research Institute, Seoul National University Hospital (2)
University of Oxford (2)
Medical Bioanalytics Institute for Ophthalmic Research Eberhard-Karls University of Tuebingen (2)
Laboratory of Tissue Engineering and Organ Regeneration, Department of Surgery, University of Geneva, Geneva, Switzerland (1)
Catholic University of Leuven, Laboratory of Clinical and Experimental Endocrinology, Leuven, Belgium (1)
Institute for Diabetes and Cancer (IDC), Helmholtz Centre Munich, German Research Center for Environmental Health, Neuherberg, Germany (1)
Center for Translational Biomedical Research, University of North Carolina at Greensboro, North Carolina Research Campus, Kannapolis, North Carolina 27402, United States; Department of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, North Carolina 28081, United States (1)
Department of Cell and Regenerative Biology Department of Chemistry Director of Mass Spectrometry Human Proteomics Program University of Wisconsin-Madison (1)
Professor i molekylærbiologi og faglig leder av PROMEC Institutt for klinisk og molekylær medisin Fakultet for medisin og helsevitenskap geir.slupphaug@ntnu.no 72573076 91825455 Laboratoriesenteret, 231.05.034, Øya, Erling Skjalgssons g 1 (1)
Laboratory of Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, Catholic University of Leuven (1)
Department of Fundamental Neurosciences University of Lausanne Rue du Bugnon 9 1005 Lausanne (1)
Department of Fundamental Neurosciences, University of Lausanne, Lausanne, Switzerland (1)
University Ghent, VIB (1)
University of Colorado Denver Anschutz Medical Campus, Department of Pharmaceutical Sciences, Colorado, USA (1)
Department of Biochemistry and Molecular Biology, University of Southern Denmark, Denmark. Campusvej 55, Odense 5230 Denmark (1)
MRC-Laboratory of Medical Sciences (1)
Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health Neuherberg, Germany (1)
Washington University (1)
Lab Head of Necker Proteomics Platform (1)
Department of Laboratory Medicine, Sahlgrenska academy, University of Gothenburg, Gothenburg, Sweden (1)
Paul & Ellen Lacy Professor of Pathology & Immunology Division of Immunobiology Washington University in St. Louis St. Louis, MO 63110 USA (1)
Washington University School of Medicine Department of Pathology & Immunology 425 S. Euclid, Campus Box 8118 St. Louis, MO 63110 (1)
Dipartimento di Medicina Veterinaria, Università degli Studi di Milano, Milano, Italy (1)
Proteomics Platform Necker, PPN-3P5, Structure federative de recherche SFR Necker, Universite Paris Descartes, Paris, FRANCE (1)
Mayo Clinic Department of Physiology and Biomedical Engineering Rochester, MN 55901 (1)
Director of Proteomics Core (1)

IsPrivate

False (11)

Modification

56.026215 (1)
59.036279 (1)
-17.026549 (1)
42.010565 (1)
15.994915 (1)

Study type

Transcription profiling by array (414)
RNA-seq of coding RNA (108)
ChIP-seq (25)
Comparative genomic hybridization by array (18)
RNA-seq of non coding RNA (10)
Methylation profiling by high throughput sequencing (9)
Methylation profiling by array (8)
Unknown experiment type (6)
Animal - High-throughput sequencing (6)
Transcription profiling by RT-PCR (6)
MicroRNA profiling by array (6)
DNA-seq (6)
ChIP-chip by array (5)
ChIP-chip by tiling array (4)
RNA-seq of total RNA (4)
ATAC-seq (3)
RNA-seq of coding RNA from single cells (3)
Cell line - High-throughput sequencing (2)
Genotyping by array (2)
MicroRNA profiling by high throughput sequencing (2)
Hi-C (2)
Other (2)
FAIRE-seq (1)
Transcription profiling by SAGE (1)
Human - High-throughput sequencing (1)
High-throughput sequencing (1)
Bisulfite-seq (1)
4C (1)
Proteomic profiling by array (1)
CUT&RUN (1)

Release Date

2022 (294)
2023 (253)
2020 (251)
2021 (248)
2025 (230)
2014 (219)
2018 (211)
2016 (200)
2015 (200)
2024 (193)
2019 (183)
2017 (165)
2013 (163)
2012 (145)
2010 (129)
2011 (111)
2009 (86)
2008 (69)
2007 (43)
2026 (31)
2006 (28)
2004 (9)
2005 (8)
2001 (6)
2000 (5)
1997 (5)
2003 (4)
1999 (3)
2002 (2)
1998 (2)

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Metabolomic Profiles of Pancreatic β-Cells and Islets Exposed to Arsenic, Islets (part-II)

Not available

ORGANISM(S): Mus musculus

ST001314 | MetabolomicsWorkbench

U13C Glucose Tracing of Young and Old Pancreatic Islets

Not available

ORGANISM(S): Mus musculus

ST000964 | MetabolomicsWorkbench

Timecourse of U13C glucose labeling of pancreatic islets in young mice

Not available

ORGANISM(S): Mus musculus

ST000965 | MetabolomicsWorkbench

Metabolomic Profiles of Pancreatic β-Cells and Islets Exposed to Arsenic, part I β-Cells

Not available

ORGANISM(S): Mus musculus

ST001266 | MetabolomicsWorkbench

Adiponectin improves local lipid metabolism in regenerating pancreatic islets after β-cell ablation

Pathways that stimulate β-cell regeneration remain of great clinical interest, yet effective therapeutic avenues that promote survival or reconstitution of β-cell mass remain elusive. Utilizing a mouse model with inducible β-cell apoptosis followed by adiponectin-mediated regeneration, we aimed to i...

ORGANISM(S): Mus musculus

2015-01-09 | E-GEOD-64787 | biostudies-arrayexpress

DNA methylation profiling of male human pancreatic islets identifies loci for type 2 diabetes

Little is known about the contribution of the epigenome to the pathophysiology of type 2 diabetes (T2D). Here we have used genome-wide DNA methylation profiling to obtain the first comprehensive DNA methylation data set for human T2D pancreatic islets. Therefore, we analyzed the methylation profile ...

ORGANISM(S): Homo sapiens

2012-04-22 | E-GEOD-21232 | biostudies-arrayexpress

Ring1b profiling in pancreatic islets

To gain insights into how pancreatic cells are programmed in vivo, we profiled RNA expression in pancreatic islets of pancreatic Ring1b conditional KO mice (conditional using a pancreas specfic Cre; Pdx1-Cre) and their littermate controls

ORGANISM(S): Mus musculus

2013-02-10 | E-MTAB-1404 | biostudies-arrayexpress

The Pdx1 Cistrome of Pancreatic Islets

We performed global location analysis of Pdx1 occupancy in mouse and human islets.

ORGANISM(S): Mus musculus

2012-05-23 | E-MTAB-1143 | biostudies-arrayexpress

Multiple Salivary Biomarkers for Early Detection of Pancreatic Cancer

Pancreatic cancer is the fourth leading cause of cancer death. Lack of early detection technology for pancreatic cancer invariably leads to a typical clinical presentation of incurable disease at initial diagnosis. Oral fluid (saliva) meets the demand for non-invasive, accessible, and highly efficie...

ORGANISM(S): Homo sapiens

2008-12-30 | E-GEOD-14245 | biostudies-arrayexpress

Genome-wide DNA methylation in normal and IUGR pancreatic islets

Intrauterine growth restriction (IUGR) increases susceptibility to age-related diseases including type 2 diabetes (T2DM), and is associated with permanent and progressive changes in gene expression and epigenetic regulation. We studied cytosine methylation throughout the genome in pancreatic islets...

ORGANISM(S): Rattus norvegicus

2010-06-24 | E-GEOD-16839 | biostudies-arrayexpress

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