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TranscriptomicsTrisomy 21 consistently activates the interferon response
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2016-07-29 | E-GEOD-79843 | biostudies-arrayexpress
TranscriptomicsshRNA cassette sequencing from disomic and trisomic fibroblasts cultured in the presence of shRNA kinome library for 14 days
Kinome-wide shRNA screen to identify kinases differentially required for survival of cells disomic and trisomic for chromosome 21 Cells were transduced in triplicate and propagated for 14 days to allow for enrichement or depletion of shRNAs from the population
ORGANISM(S): Homo sapiens 
2016-07-29 | E-GEOD-79840 | biostudies-arrayexpress
TranscriptomicsRNAseq from disomic and trisomic fibroblasts and lymphoblastoids
RNA was sequenced from individuals Disomic and Trisomic for chromosome 21 to identify consistent changes in gene expression across individuals Cells were cultured at subconfluency and RNA harvested for sequencing
ORGANISM(S): Homo sapiens 
2016-07-29 | E-GEOD-79842 | biostudies-arrayexpress
TranscriptomicsRNAseq from Dp16 and control mice
RNA was sequenced from Normal and DP 16 mice to identify consistent changes in gene expression across cohorts Cells were cultured at subconfluency and RNA harvested for sequencing
ORGANISM(S): Mus musculus 
2016-07-29 | E-GEOD-84526 | biostudies-arrayexpress
TranscriptomicsPolyA RNAseq from HCT116 cells in normoxia and hypoxia
To determine the effects of depleting TIP60, CDK8, or HIF1A on the transcriptional response to hypoxia, we performed RNAseq analysis of four HCT116 colorectal carcinoma cell lines (shNT, HIF1A-/-, shTIP60 and shCDK8) in normoxic and hypoxic (24hrs, 1% O2) conditions. PolyA RNA for two independent bi...
ORGANISM(S): Homo sapiens 
2016-06-02 | E-GEOD-68297 | biostudies-arrayexpress
GenomicsWhole-exome sequencing of ovarian clear cell carcinoma in clinical outliers
Whole-exome sequencing dataset for the Australian Ovarian Cancer Study (AOCS) and The Jikei University School of Medicine (JIKEI) ovarian clear cell carcinoma (OCCC) clinical outliers project, representing 10 donors. Although OCCC are commonly resistant to platinum based chemotherapy, good clinical ...
EGAS00001004248 | EGA
TranscriptomicsRNAseq from disomic and trisomic T cells and monocytes
RNA was sequenced from Disomic and Trisomic individuals for chromosome 21 to identify consistent changes in gene expression across individuals Cells were cultured at subconfluency and RNA harvested for sequencing
ORGANISM(S): Homo sapiens 
2016-07-29 | E-GEOD-84531 | biostudies-arrayexpress
Genomicsc206f97a-4770-4337-a7bd-0bf63eede603 - samples
Whole-exome sequencing dataset for the Australian Ovarian Cancer Study (AOCS) and The Jikei University School of Medicine (JIKEI) ovarian clear cell carcinoma (OCCC) clinical outliers project, representing 10 donors. Consists of 20 fastq files: one normal and one tumour from each patient.
EGAD00001006004 | EGA
GenomicsPeter MacCallum Cancer Centre Research Data Access Committee
Data Access Committee EGAC00001001500
EGAC00001001500 | EGA
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