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TranscriptomicsCoordination of frontline defense mechanisms under severe oxidative stress.
Oxidative stress (OS) results from genetic defects or stressful environmental challenges that cause unchecked production of reactive oxygen species (ROS). OS has been implicated in many diseases due to its wide ranging damage to nucleic acids, proteins and lipids. Using Halobacterium salinarum NRC...
ORGANISM(S): Halobacterium salinarum 
2010-05-26 | E-GEOD-17515 | biostudies-arrayexpress
UnknownANKRD49 promotes the metastasis of NSCLC via activating JNK-ATF2/c-Jun-MMP-2/9 axis.
Not available
S-EPMC10644579 | biostudies-literature
UnknownReduced miR-200b and miR-200c expression contributes to abnormal hepatic lipid accumulation by stimulating JUN expression and activating the transcription of srebp1.
Not available
S-EPMC5094994 | biostudies-literature
UnknownDataset of active avoidance in Wistar-Kyoto and Sprague Dawley rats: Experimental data and reinforcement learning model code and output.
Not available
S-EPMC7451822 | biostudies-literature
UnknownKaempferol Mitigates <i>Pseudomonas aeruginosa</i>-Induced Acute Lung Inflammation Through Suppressing GSK3β/JNK/c-Jun Signaling Pathway and NF-κB Activation.
Not available
S-EPMC11944347 | biostudies-literature
UnknownTelmisartan directly ameliorates the neuronal inflammatory response to IL-1β partly through the JNK/c-Jun and NADPH oxidase pathways.
Not available
S-EPMC3410820 | biostudies-literature
MetabolomicsBranched-chain ketoacids derived from cancer cells modulate macrophage polarization and metabolic reprogramming

Macrophages are prominent immune cells in the tumor microenvironment that can be educated into pro-tumoral phenotype by tumor cells to favor tumor growth and metastasis. The mechanisms that mediate a mutualistic relationship between tumor cells and macrophages remain poorly characterized. Here, w...

2022-10-03 | MTBLS4497 | MetaboLights
TranscriptomicsHalobacterium salinarum NRC-1 total RNA hybridization of TFBd overexpression versus Reference sample
Total RNA hybridizations of Halobacterium salinarum NRC-1 total RNA versus a strain overexpressing TFBd were compared to verify the transcriptome landscape changes. Comparison with TFBd binding sites localized using ChIP-chip data and MeDiChI algorithm (Reiss et al, 2008) allowed observation that TF...
ORGANISM(S): Halobacterium sp. NRC-1 
2010-05-17 | E-GEOD-15788 | biostudies-arrayexpress
TranscriptomicsHalobacterium growth in standard growth media: time course
We report detailed characterization of physiological changes encoded by 63% of all genes within the archaeon Halobacterium salinarum subsp. NRC-1 during routine laboratory growth. While the majority of these changes occur during the transition from rapid exponential growth to the stationary phase, ...
ORGANISM(S): Halobacterium sp. NRC-1 
2010-05-14 | E-GEOD-14832 | biostudies-arrayexpress
TranscriptomicsHalobacterium salinarum NRC-1 growth curve
Halobacterium salinarum NRC-1 was grown in CM media, at 37oC in a waterbath with agitation of 125 rpm under constant light. Analysis of transcriptional changes during growth, in addition to mapping of transcriptome structure under the same conditions, provided interesting insights about regulatory l...
ORGANISM(S): Halobacterium sp. NRC-1 
2010-05-17 | E-GEOD-12977 | biostudies-arrayexpress
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