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ProteomicsmRNA Tethered Ribosome Interactome Profiling (mTRIP): A method for Identifying Trans-Acting Factors on Ribosome-Bound mRNA in Yeast
Translation initiation in eukaryotes is a tightly regulated process that ensures accurate recognition of the AUG start codon. However, certain mRNAs can utilize non-AUG codons such as UUG for initiation. In the Glycine tRNA Synthetase 1 (Grs1) mRNA both AUG and UUG serve as translation start sites. ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2026-10-06 | PXD070638 | Pride
Ribosome Translation Mrna Grs1 Initiation factors 
ProteomicsAltered proteome in translationinitiation fidelity defective eIF5G31R mutant causes oxidative stress and DNA damage
The recognition of AUG start codon and selection of the open reading frame (ORF) is fundamental to protein biosynthesis. Defect in the start codon selection adversely affectproteome and have a pleiotropic effect on cellular function. Using proteomic techniques, we identified differential protein exp...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-05-19 | PXD029460 | Pride
Sui¯ phenotype Translation initiation Eif5 Proteomics Itraq 
TranscriptomicsExpression analysis of C. elegans wild-type N2 and rsks-1, daf-2, daf-2 rsks-1 and daf-16; daf-2 rsks-1 mutants
Investigation of whole genome gene expression level changes in C. elegans rsks-1, daf-2, daf-2 rsks-1 and daf-16; daf-2 rsks-1 mutant compared to the wild-type N2 strain. The mutants have altered longevity phenotypes. The mutants analyzed in this study are further described in Di Chen, Patrick Wai-...
ORGANISM(S): Caenorhabditis elegans 
2013-11-14 | E-GEOD-52340 | biostudies-arrayexpress
TranscriptomicsRNA-seq of multiple tissue types and developmental stages of Salvia hispanica (chia)
Salvia hispanica L. (chia) is a member of the mint family that is cultivated for its seeds. The majority of seed content in chia is comprised of omega fatty acids. Furthermore, chia seeds are also rich in fiber and minerals. The human health potential of chia seeds have driven studies of dietary eff...
ORGANISM(S): Salvia hispanica 
2020-01-01 | E-MTAB-5515 | biostudies-arrayexpress
TranscriptomicsExpression analysis of C. elegans wild-type N2 and rsks-1, daf-2, daf-2 rsks-1 and daf-16; daf-2 rsks-1 mutants
Investigation of whole genome gene expression level changes in C. elegans rsks-1, daf-2, daf-2 rsks-1 and daf-16; daf-2 rsks-1 mutant compared to the wild-type N2 strain. The mutants have altered longevity phenotypes. The mutants analyzed in this study are further described in Di Chen, Patrick Wai-L...
ORGANISM(S): Caenorhabditis elegans 
2013-11-14 | GSE52340 | GEO
UnknownA Comprehensive Gene Expression Profile of Pectin Degradation Enzymes Reveals the Molecular Events during Cell Wall Degradation and Pathogenesis of Rice Sheath Blight Pathogen Rhizoctonia solani AG1-IA.
Not available
S-EPMC7345747 | biostudies-literature
TranscriptomicsExpression profiling of cerebellar granule neurons from Rattus norvegicus cultured for four weeks
Expression analysis was performed with in vitro cultured cerebellar granule neurons (CGNs) isolated from rat brain. The CGNs were culture for four weeks. Each sample was collected after interval of seven days. No treatment was given to any cultured neurons at any time point. The purpose of the exper...
ORGANISM(S): Rattus norvegicus 
2016-03-07 | E-MTAB-4552 | biostudies-arrayexpress
UnknownNitric oxide monooxygenation (NOM) reaction of cobalt-nitrosyl {Co(NO)}8 to CoII-nitrito {CoII(NO2 -)}: base induced hydrogen gas (H2) evolution.
Not available
S-EPMC8159239 | biostudies-literature
UnknownIdentifying RAGE inhibitors as potential therapeutics for Alzheimer's disease via integrated in-silico approaches.
Not available
S-EPMC12098779 | biostudies-literature
UnknownIdentification of Potent HDAC6 Inhibitors for Breast Cancer Through Multi-Stage In Silico Modeling.
Not available
S-EPMC12461084 | biostudies-literature
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