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ProteomicsHuman Pap test LC-MS/MS metaproteomics
The human cervical-vaginal area contains proteins derived from microorganisms that may prevent or predispose women to gynecological conditions. The liquid Pap test fixative is an unexplored resource for analysis of microbial communities and the microbe-host interaction. Previously, we showed that th...
ORGANISM(S): Homo sapiens (Human) 
2018-07-23 | PXD009596 | Pride
Pap test Microbiome Metaproteomics 
TranscriptomicsTranscription profiling of blood from human pituitary adenoma predisposition (PAP) patients to characterize the genetic basis of low penetrance tumor susceptibility
While identification of genes mutated in high penetrance tumor predisposition syndromes has been a success story, much less progress has been made in characterizing the genetic basis of low penetrance tumor susceptibility. Combining recently introduced chip-based technologies with traditional geneal...
ORGANISM(S): Homo sapiens 
2007-11-11 | E-GEOD-4488 | biostudies-arrayexpress
TranscriptomicsInterference of B-Cell and T-Cell Receptor Genes in Single-Cell RNA Sequencing Data
B and T cells play central roles in immune responses and, as such, are integral in many diseases, such as autoimmunity. Characterizing these cells, their subsets, and exploring their transcriptomes to understand the underlying biology, can be achieved using single-cell RNA sequencing (scRNA-seq). Wh...
ORGANISM(S): Homo sapiens 
2025-12-16 | E-MTAB-12346 | biostudies-arrayexpress
UnknownNovel PAP-targeted CAR-T therapy enhances antitumor efficacy through CoupledCAR approach.
Not available
S-EPMC12161386 | biostudies-literature
TranscriptomicsInsights into the transcriptomics of polyphagy: Bemisia tabaci adaptability to phenylpropanoids involves coordinated expression of defense and metabolic genes
Background: The whitefly Bemisia tabaci is a major generalist agricultural pest of field and horticultural crops world-wide. Despite its importance, the molecular bases of defense mechanisms in B. tabaci against major plant secondary defense compounds, such as the phenylpropanoids, remain unknown. R...
ORGANISM(S): Bemisia tabaci 
2012-09-01 | E-GEOD-31569 | biostudies-arrayexpress
UnknownA Mutated Prostatic Acid Phosphatase (PAP) Peptide-Based Vaccine Induces PAP-Specific CD8+ T Cells with Ex Vivo Cytotoxic Capacities in HHDII/DR1 Transgenic Mice.
Not available
S-EPMC9032647 | biostudies-literature
UnknownTargeting effector memory T cells with the small molecule Kv1.3 blocker PAP-1 suppresses allergic contact dermatitis.
Not available
S-EPMC1929164 | biostudies-literature
UnknownSecretome screening reveals immunomodulating functions of IFNα-7, PAP and GDF-7 on regulatory T-cells.
Not available
S-EPMC8373891 | biostudies-literature
TranscriptomicsTranscription repressor Bach2 is required for pulmonary surfactant homeostasis and alveolar macrophage function.
Pulmonary alveolar proteinosis (PAP) results from a dysfunction of alveolar macrophages (AMs), chiefly due to disruptions in the signaling of granulocyte macrophage colony-stimulating factor (GM-CSF). We found that mice deficient for the B lymphoid transcription repressor BTB and CNC homology 2 (Bac...
ORGANISM(S): Mus musculus 
2014-01-15 | E-GEOD-54050 | biostudies-arrayexpress
UnknownPrime-boost vaccination targeting prostatic acid phosphatase (PAP) in patients with metastatic castration-resistant prostate cancer (mCRPC) using Sipuleucel-T and a DNA vaccine.
Not available
S-EPMC5850960 | biostudies-literature
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