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ProteomicsA new role for the DEAD-box RNA helicase DDX3 in co-translational protein quality control
DEAD-box RNA helicases are central players in RNA metabolism, however, their role in translation regulation is largely unexplored in parasitic protozoa. Here, we have investigated the role of DDX3 RNA helicase in ribosome-associated protein quality control in Leishmania. We show that ribosomes move ...
ORGANISM(S): Leishmania infantum 
2021-07-23 | PXD020667 | Pride
Ribosome Leishmania infantum Ddx3 Label-free quantitative proteomics Cotranslational protein ubiquitination Orbitrap fusion 
TranscriptomicsWhole-genome comparative RNA expression profiling of axenic and intracellular amastigote forms of Leishmania infantum
Transcriptional analysis of L. infantum promastigote compared to L. infantum intracellular amastigote and transcriptional analysis of L. infantum promastigote compared to L. infantum axenic amastigote. The full-genome DNA microarrays includes one 70-oligonucleotides probe for each gene of L.infantum...
ORGANISM(S): Leishmania infantum 
2010-05-14 | E-GEOD-13983 | biostudies-arrayexpress
ProteomicsFunctional characterization of the p97/valosin-containing protein (VCP) interacting network in Leishmania Functional characterization of the p97/valosin-containing protein (VCP) interacting network in Leishmania
Valosin‐containing protein (VCP)/p97/Cdc48 is an essential AAA+ ATPase associated with many ubiquitin-dependent cellular pathways that plays a central role in protein quality control in all eukaryotes. Its functional diversity relies on its ability to cooperate with a large number of protein cofacto...
ORGANISM(S): Leishmania infantum JPCM5 
2020-08-06 | PXD013731 | Pride
Leishmania  vcp/p97  vcp cofactors  co-immunoprecipitation  lc-ms/ms  network proteomics 
TranscriptomicsTranscriptional analysis of wild-type Leishmania species between both stages using full-genome DNA microarrays
Transcriptional analyses of L. infantum promastigote compared to L. infantum intracellular amastigote, and L. major promastigote compared to L. major intracellular amastigote The full-genome DNA microarray includes one 70mer-oligonucleotide probe for each gene of L. infantum and for each gene of L....
ORGANISM(S): Leishmania major 
2008-05-28 | E-GEOD-10407 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of strains of Leishmania infantum, Leishmania major and Leishmania tarentolae
The genomic DNAs of strains JPCM5 and 263 of L. infantum, strains LV39 and Friedlin of L. major and strains Parrot-TarII and S125 of L. tarentolae were used in comparative genomic hybridizations to reveal the intra-species and inter-species gene content, and to validate L. tarentolae Parrot-TarII ge...
ORGANISM(S): Leishmania tarentolae 
2011-10-20 | E-GEOD-27184 | biostudies-arrayexpress
UnknownSARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.
Not available
S-EPMC7995808 | biostudies-literature
UnknownTiming of surgery following SARS-CoV-2 infection: an international prospective cohort study.
Not available
S-EPMC8206995 | biostudies-literature
UnknownSARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study.
Not available
S-EPMC8652887 | biostudies-literature
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