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TranscriptomicsTranscriptomes in Healthy and Diseased Gingival Tissues
We examined gene expression signatures in healthy and diseased gingival tissues in 90 patients. Analysis of the gingival tissue transcriptome in states of periodontal health and disease may reveal novel insights of the pathobiology of periodontitis. Keywords: gingival tissue disease state analysis N...
ORGANISM(S): Homo sapiens 
2008-12-22 | E-GEOD-10334 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of gingival tissue from patients with periodontitis: Bacterial Correlates of Gingival Gene Expression
We investigated the association between subgingival bacterial profiles and gene expression patterns in gingival tissues of patients with periodontitis. A total of 120 patients undergoing periodontal surgery contributed with a minimum of two interproximal gingival papillae (range 2-4) from a maxillar...
ORGANISM(S): Homo sapiens 
2009-12-21 | E-GEOD-16134 | biostudies-arrayexpress
TranscriptomicsAcute venous hypertension induces local release of inflammatory cytokines and endothelial activation in humans
Background: Venous hypertension is often present in advanced and in acute decompensated heart failure (HF). However, it is unclear whether high intravenous pressure can cause alterations in homeostasis by promoting inflammation and endothelial cell (EC) activation. We used an experimental model of a...
ORGANISM(S): Homo sapiens 
2013-12-04 | E-GEOD-38783 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human peripheral blood monocytes in periodontal therapy
Periodontal infections have been associated with systemic inflammation and risk for atherosclerosis and vascular disease. We investigated the effects of comprehensive periodontal therapy on gene expression of peripheral blood monocytes. Approximately 1/3 of the patients showed substantial changes in...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-6751 | biostudies-arrayexpress
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