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TranscriptomicsNovel male-biased expression in paralogs of the aphid slilmfast nutrient amino acid transporter expansion
A major goal of molecular evolutionary biology is to understand the fate and consequences of duplicated genes. In this context, aphids are particularly intriguing because the newly sequenced pea aphid genome is characterized by extraordinarily high levels of lineage-specific gene duplication relativ...
ORGANISM(S): Myzus persicae 
2011-09-13 | E-GEOD-31024 | biostudies-arrayexpress
ProteomicsDuplicated ribosomal protein paralogs promote alternative translation and drug resistance
Ribosomes are often seen as monolithic machines produced from uniformly regulated genes. However, in yeast most ribosomal proteins come from duplicated genes. Here, we demonstrate that gene duplication may serve as a stress-adaptation mechanism modulating the global proteome through the differential...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-08-09 | PXD033843 | Pride
Drpg Saccharomyces cerevisiae Paralogs 
GenomicsSelective translation mechanism through two paralogs of eukaryotic initiation factor 4A
Selective translation mechanism through two paralogs of eukaryotic initiation factor 4A
PRJNA521496 | ENA
ProteomicsThe Functions of the COPII Gene Paralogs SEC23A and SEC23B Are Interchangeable In Vivo
This dataset includes BioID for SEC23A and SEC23B. The paper describes the functional redundancy of these two gene paralogs in the context of human disease.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-11-09 | MSV000081703 | MassIVE
GenomicsRibosome profiling in DDX3X degron cell lines and complementation with sex-linked paralogs
Ribosome profiling in DDX3X degron cell lines and complementation with sex-linked paralogs
PRJNA749053 | ENA
ProteomicsParalog protein compensation preserves protein-protein interaction networks following gene loss cancer
Abstract Proteins operate within dense interconnected networks, where interactions are necessary both for stabilising proteins and enabling them to execute their molecular functions. Remarkably, the protein-protein interaction networks operating within tumour cells continue to function despite wide...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD055643 | Pride
Protein-protein interaction Compensation Paralog protein Cancer. 
GenomicsActivating PAX Gene Family Paralogs to Complement PAX5 Leukemia Driver Mutations
Activating PAX Gene Family Paralogs to Complement PAX5 Leukemia Driver Mutations
PRJNA432203 | ENA
GenomicsAsymmetry and redundancy of STAT5 paralogs across CD8+ T cell differentiation states
Asymmetry and redundancy of STAT5 paralogs across CD8+ T cell differentiation states
PRJNA1425165 | ENA
GenomicsDuplicated ribosomal protein paralogs promote alternative translation and drug resistance
Duplicated ribosomal protein paralogs promote alternative translation and drug resistance
PRJNA837278 | ENA
GenomicsOrigins and division of labor in trypanosome RNA processing through expanded Mex67 paralogs
Origins and division of labor in trypanosome RNA processing through expanded Mex67 paralogs
PRJNA998728 | ENA
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