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Short hairpin RNA (shRNA) expression strategies that allow safe and persistent target mRNA knockdown are key to the success of many in vitro or in vivo RNAi applications. Here, we propose a novel solution which is expression of a promoterless miRNA-adapted shRNA (shmiRNA) from an engineered genomic ...
Bam files for 124 samples (62 tumor vs blood pairs); Whole Genome Sequencing performed on Illumina HiSeq X Ten
Whole Genome Sequencing of Huh7 cell lines
Data Access Committee EGAC00001000346
Bam files for 16 meningioma tumor samples; ChIPseq performed on Illumina HiSeq 2000
DNA methylation patterns delineate clinically relevant subgroups of meningioma. We previously established the six meningioma methylation classes (MC) benign-1, 2, 3, intermediate-A, B and malignant. Here, we set out to identify subgroup-specific mutational patterns and pathway regulation. Whole-gen...
WGS data of medulloblastoma tumor/control pairs.
WGS data of medulloblastoma tumor/control pairs.
WGS data of medulloblastoma tumor/control pairs.
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