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TranscriptomicsThe Role of PTHrP in Osteoblast Response to Microgravity: Implications for Osteoporosis Development.
Prolonged skeletal unloading through bedrest results in bone loss similar to that observed in elderly osteoporotic patients, but with an accelerated timeframe. This rapid effect on weight-bearing bones is also observed in astronauts who lose up to 2% of their bone mass per month spent in Space. Des...
ORGANISM(S): Mus musculus 
2016-08-09 | E-GEOD-78980 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human breast cancer MDA-MB-231 cells treated with PTHrP and control siRNA
Parathyroid hormone-related protein (PTHrP) is overexpressed in many cancer types. This secretory protein can induce hypercalcaemia of malignancy by mimicking the action of calcium-regulating parathyroid hormone (PTH). PTHrP may also be involved in the regulation of migration, invasion, proliferatio...
ORGANISM(S): Homo sapiens 
2007-12-12 | E-GEOD-4292 | biostudies-arrayexpress
UnknownA parathyroid hormone related supramolecular peptide for multi-functionalized osteoregeneration.
Not available
S-EPMC10792172 | biostudies-literature
TranscriptomicsAnalysis of Gene Expression in PTHrP-/- Mammary Buds
Analysis of Gene Expression in PTHrP-/- Mammary Buds Supports a Role for BMP Signaling and MMP2 in the Initiation of Ductal Morphogenesis. Parathyroid hormone-related protein (PTHrP) acts on the mammary mesenchyme and is required for proper embryonic mammary development. In order to understand PTHrP...
ORGANISM(S): Mus musculus 
2009-08-15 | E-GEOD-17654 | biostudies-arrayexpress
UnknownParathyroid hormone-related peptide and parathyroid hormone-related peptide receptor type 1 in locally advanced laryngeal cancer as prognostic indicators of relapse and survival.
Not available
S-EPMC9235225 | biostudies-literature
TranscriptomicsPTHrP Induces STAT5 Activation, Secretory Differentiation and Mammary Tumor Progression
Parathyroid hormone-related protein (PTHrP) is required for embryonic breast development and has important functions during lactation, when it is produced by alveolar epithelial cells and secreted into the maternal circulation to mobilize skeletal calcium used for milk production. PTHrP is also prod...
ORGANISM(S): Mus musculus 
2021-12-10 | E-MTAB-11281 | biostudies-arrayexpress
UnknownTargeted expression of constitutively active receptors for parathyroid hormone and parathyroid hormone-related peptide delays endochondral bone formation and rescues mice that lack parathyroid hormone-related peptide.
Not available
S-EPMC28367 | biostudies-literature
UnknownA Recombinant Parathyroid Hormone-Related Peptide Locally Applied in Osteoporotic Bone Defect.
Not available
S-EPMC10401080 | biostudies-literature
UnknownDecoding migraine disorders: parathyroid hormone-related peptide receptors as key genetic drivers.
Not available
S-EPMC12034459 | biostudies-literature
UnknownEarly Addition of Parathyroid Hormone-Related Peptide Regulates the Hypertrophic Differentiation of Mesenchymal Stem Cells.
Not available
S-EPMC8804866 | biostudies-literature
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