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LARS undergoes structural changes in response to amino acid stimulation and translocates to lysosome, exhibiting non-canonical functions such as mTORC1 activation instead of its canonical function of tRNA amino-acylation. This study investigates which post-translational modifications (PTMs) of LARS ...
ORGANISM(S): Homo sapiens (Human) 
2026-04-06 | PXD066801 | Pride
Macrophages represent a major immune cell population in atherosclerotic plaques and play central role in the progression of this lipid-driven chronic inflammatory disease. Targeting immunometabolism is proposed as a strategy to revert aberrant macrophage activation to improve disease outcome. Here, ...
2021-03-05 | MTBLS2159 | MetaboLights
We used the MPSS technology to uncover gene expression profiling in a greater depth in the early embryonic gonads and primordial germ cells (PGCs) in the chicken. Total numbers of sequenced signatures were 1,012,533 and 995,676 for the PGCs and gonad. Using a false discovery rate cut-off of 0.05, we...
ORGANISM(S): Gallus gallus 
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