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UnknownThe complete chloroplast genome sequence of Magic Lily (Lycoris squamigera).
Magic Lily (Lycoris squamigera), belonging to the Amaryllidaceae family, is cultivated for ornamental and medicinal purposes. To characterize its genomic information, we obtained the complete chloroplast genome sequence of L. squamigera by assembling Illumina whole genome sequence data...
S-EPMC7799502 | biostudies-literature
Genomics97dd9532-0482-4bf1-ad1d-fb976b8ed7ea - samples
This dataset contains whole-genome sequencing data files from colon organoid cultures, which were mutated using CRISPR-Cas9 for specific genes (APC, KRAS, TP53 and SMAD4) to generate in vitro transformed cancer cells. After introducing each mutation, the resulting cultures were subjected to whole-ge...
EGAD00001002719 | EGA
GenomicsWhole genome sequencing of colon organoid cultures with artificially induced oncogenic mutations
Using the CRISPR-Cas9 genome editing system, various oncogenic mutations were introduced in the genome of normal adult stem cells derived from the colon. The resulting clonal cultures were subjected to whole genome sequencing. In addition, the cultures were transplanted in a mouse and the resulting ...
EGAS00001001969 | EGA
GenomicsDivision of Biomedical Genetics UMC Utrecht
Data Access Committee EGAC00001000432
EGAC00001000432 | EGA
UnknownCyclic swelling enabled, electrically conductive 3D porous structures for microfluidic urinalysis devices.
Urinalysis is a simple and non-invasive approach for the diagnosis and monitoring of organ health and also is often used as a facile technique in assessment of substance abuse. However, quantitative urinalysis is predominantly limited to clinical laboratories. Here, we present an electrical sensing ...
S-EPMC10153631 | biostudies-literature
UnknownpH-dependent mechanism of oxygen evolution in highly disordered RuO<sub>2</sub> nanosheets.
Amorphous materials have garnered significant research interest because of their high structural tolerances and useful functionalities. Here, we develop an effective synthesis method for atomically thin, highly disordered RuO2 nanosheets that exhibit a promising electrocatalytic performan...
S-EPMC12820091 | biostudies-literature
UnknownPreclinical assessment of thrombin-preconditioned human Wharton's jelly-derived mesenchymal stem cells for neonatal hypoxic-ischaemic brain injury.
Hypoxic-ischaemic encephalopathy (HIE) is a type of brain injury affecting approximately 1 million newborn babies per year worldwide, the only treatment for which is therapeutic hypothermia. Thrombin-preconditioned mesenchymal stem cells (MSCs) exert neuroprotective effects by enriching cargo conten...
S-EPMC8581315 | biostudies-literature
ProteomicsA mitochondrial proteome profile of type 2 diabetes mellitus in skeletal muscles
The goal of the project is to understand the mitochondrial proteome profiles related to T2DM. We performed comprehensive proteome profiling of mitochondria isolated from skeletal muscles in nine T2DM patients and nine control subjects with normal glucose tolerance (NGT).
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-03-13 | MSV000083560 | MassIVE
UnknownComparison of Iohexol-380 and Iohexol-350 for Coronary CT Angiography: A Multicenter, Randomized, Double-Blind Phase 3 Trial.

Objective

This multi-center, randomized, double-blind, phase 3 trial was conducted to compare the safety and efficacy of contrast agents iohexol-380 and iohexol-350 for coronary CT angiography in healthy subjects.

Materials and methods

Volunteers were randomized to receive 420 mgI/kg ...
S-EPMC4842853 | biostudies-literature
UnknownNatural form of noncytolytic flexible human Fc as a long-acting carrier of agonistic ligand, erythropoietin.
Human IgG1 Fc has been widely used as a bioconjugate, but exhibits shortcomings, such as antibody- and complement-mediated cytotoxicity as well as decreased bioactivity, when applied to agonistic proteins. Here, we constructed a nonimmunogenic, noncytolytic and flexible hybrid Fc (hyFc) consisting o...
S-EPMC3174958 | biostudies-literature
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