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ProteomicsIntegrative proteomics and transcriptomics of human T-cells reveals temporal changes in metabolic pathways following TCR-mediated activation
T-cells are a critical component of the adaptive immune system and play a key role in immunological surveillance. Upon engagement of T-cell receptor (TCR), CD4+ and CD8+ T-cells acquire effector functions through a complex interplay between mRNA and proteins yet to be fully understood. In this study...
ORGANISM(S): Homo sapiens (Human) 
2023-12-28 | PXD038810 | Pride
Human t cell activation Dda proteomics Cd8+ t cells Cd4+ t cells 
ProteomicsCharacterization of human pineal gland proteome
Pineal gland is a neuroendocrine gland located at the center of the brain. It protects the body from the effect of toxic compounds and regulates sleep-wake cycle, body temperature and sexual maturity through the secretion of melatonin. Abnormal functioning of pineal glands is known to be associat...
ORGANISM(S): Homo sapiens (Human) 
2017-02-02 | PXD004332 | Pride
Human Gland Tissue Pineal Lc-ms/ms 
ProteomicsProteogenomics of Candida tropicalis – an opportunistic pathogen
Candida tropicalis is an opportunistic pathogen which causes candidiasis in immune-compromised individuals. It is one of the members of the non-albicans group of Candida that are known to be azole resistant and is frequently seen in individuals being treated for cancers, HIV-infection and bone-marr...
ORGANISM(S): Candida tropicalis (Yeast) 
2017-05-08 | PXD001071 | Pride
Genome annotation Shotgun proteomics 
UnknownMassively parallel knock-in engineering of human T cells.
Not available
S-EPMC11260498 | biostudies-literature
UnknownImmunogenetic metabolomics revealed key enzymes that modulate CAR-T metabolism and function.
Not available
S-EPMC10055032 | biostudies-literature
UnknownResistin enhances the expansion of regulatory T cells through modulation of dendritic cells.
Not available
S-EPMC2914082 | biostudies-literature
UnknownSynthesis of Titanium Silicalite-1 with High Catalytic Performance for 1-Butene Epoxidation by Eliminating the Extraframework Ti.
Not available
S-EPMC6640744 | biostudies-literature
UnknownRobust tumor immunity to melanoma mediated by interleukin-9-producing T cells.
Not available
S-EPMC3518666 | biostudies-literature
UnknownSkin CD4(+) memory T cells exhibit combined cluster-mediated retention and equilibration with the circulation.
Not available
S-EPMC4866325 | biostudies-literature
ProteomicsGenetic aberrations in MAP kinase pathway play an important role in erlotinib resistance in head and neck cancer
Epidermal growth factor receptor (EGFR), a receptor tyrosine kinase is overexpressed in 90% of Head and neck squamous cell carcinoma (HNSCC) patients. Clinical trials with EGFR-targeted tyrosine kinase inhibitors such as erlotinib have shown a modest activity in HNSCC alternate mechanisms of resist...
ORGANISM(S): Homo sapiens (Human) 
2019-12-18 | PXD007785 | Pride
Head and neck cancer Mass spectrometry Signaling pathways Quantitative phosphoproteomics Egfr-tyrosine kinase inhibitor resistance 
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