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TranscriptomicsTranscription profiling of melanized domamine neurons isolated from male and female patients with Parkinson disease to investigate gender differences
We used 500 melanized dopamine neurons isolated from post-mortem human substantia nigra pars compacta of each sample with laser capture microdissection. Total RNA was extracted with Arcturus PicoPure RNA extraction kit and amplified two times with Arcturus RiboAmp RNA amplification kit. the samples ...
ORGANISM(S): Homo sapiens 
2008-01-19 | E-MEXP-1416 | biostudies-arrayexpress
UnknownApplication of Multigene Panel Sequencing in Patients with Prolonged Rate-corrected QT Interval and No Pathogenic Variants Detected in KCNQ1, KCNH2, and SCN5A.
Not available
S-EPMC5700148 | biostudies-literature
MetabolomicsTwo Poplar-Associated Bacterial Isolates Induce Additive Favorable Responses in a Constructed Plant-Microbiome System
The biological function of the plant-microbiome system is the result of contributions from the host plant and microbiome members. The Populus root microbiome is a diverse community that has high abundance of β- and γ-Proteobacteria, both classes which include multiple plant-growth promoting represen...
2017-07-25 | MTBLS332 | MetaboLights
UnknownRed seaweed extracts reduce methane production by altering rumen fermentation and microbial composition in vitro.
Not available
S-EPMC9709288 | biostudies-literature
UnknownCombining common genetic variants and non-genetic risk factors to predict risk of cutaneous melanoma.
Not available
S-EPMC6240742 | biostudies-literature
UnknownNivolumab for Metastatic Renal Cell Carcinoma: Results of a Randomized Phase II Trial.
Not available
S-EPMC4806782 | biostudies-literature
UnknownCrowd-sourced machine learning prediction of long COVID using data from the National COVID Cohort Collaborative.
Not available
S-EPMC11462169 | biostudies-literature
ProteomicsAlzheimer's disease proteomics
This project aims to determine how the brain proteome is remodeled in Alzheimer's disease (AD). AD is pathologically characterized by an accumulation of insoluble aggregates composed of Abeta peptides in the brain and is clinically characterized by progressive memory impairment. While the precise pa...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2016-12-19 | MSV000080431 | MassIVE
GenomicsProstate Cancer Genome Sequencing Project

Prostate cancer is a prevalent cause of cancer morbidity and mortality in men. In order to characterize the full range of somatic mutations in protein-coding genes that may drive the growth of prostate cancer, we sequenced the exonic regions of genomic and tumor DNA from over 100 patients with hi...

phs000447.v1.p1 | EGA
GenomicsThe Genomic Complexity of Primary Human Prostate Cancer

Seven primary prostate cancers and their paired normal counterparts were DNA-sequenced on a massively parallel sequencing platform. This approach was taken to investigate the genomes for mutations and genomic alterations that would be undetectable by lower-resolution methods. As result, tumor...

phs000330.v1.p1 | EGA
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