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GenomicsH2A.Z inheritance during the cell cycle and its impact on promoter organization and dynamics [ChIP-seq]
While it has been clearly established that well positioned H2A.Z-containing nucleosomes flank the nucleosome depleted region (NDR) at the transcriptional start site (TSS) of active mammalian genes, how this chromatin-based information is transmitted through the cell cycle is unknown. We show here th...
ORGANISM(S): Mus musculus 
2012-11-23 | E-GEOD-41371 | biostudies-arrayexpress
TranscriptomicsTime series expression data following miR-9 inhibition
A high-resolution time series study of transcriptome dynamics following antimiR--mediated inhibition of miR-9 in a Hodgkin lymphoma cell-line revealed both general and miR-9 specific aspects of the miRNA--mediated post--transcriptional dynamic response.MiR-9 inhibition induced a multiphasic gene re...
ORGANISM(S): Homo sapiens 
2015-06-06 | E-GEOD-52710 | biostudies-arrayexpress
TranscriptomicsStable Patterns of Gene Expression Regulating Carbohydrate Metabolism Determined by Geographic Ancestry
Individuals of African descent in the United States suffer disproportionately from diseases with a metabolic etiology (obesity, metabolic syndrome, and diabetes), and from the pathological consequences of these disorders (hypertension and cardiovascular disease). Using a combination of genetic/geno...
ORGANISM(S): Homo sapiens 
2009-10-30 | E-GEOD-12959 | biostudies-arrayexpress
TranscriptomicsStudies of canine breed development on the island of Sardinia recapitulate genomic features of human population isolates [COO]
The Italian island of Sardinia is well known in studies of human population isolates. It is also home to the Fonni's Dog, a breed of canine whose development was reliant on the functionality of the dog. Using genome-wide variant and sequence analyses, we have characterized the Fonni's Dog relative t...
ORGANISM(S): Canis lupus familiaris 
2016-06-10 | E-GEOD-83151 | biostudies-arrayexpress
TranscriptomicsStudies of canine breed development on the island of Sardinia recapitulate genomic features of human population isolates [MEDI]
The Italian island of Sardinia is well known in studies of human population isolates. It is also home to the Fonni's Dog, a breed of canine whose development was reliant on the functionality of the dog. Using genome-wide variant and sequence analyses, we have characterized the Fonni's Dog relative t...
ORGANISM(S): Canis lupus familiaris 
2016-06-10 | E-GEOD-83154 | biostudies-arrayexpress
TranscriptomicsStudies of canine breed development on the island of Sardinia recapitulate genomic features of human population isolates [CANE]
The Italian island of Sardinia is well known in studies of human population isolates. It is also home to the Fonni's Dog, a breed of canine whose development was reliant on the functionality of the dog. Using genome-wide variant and sequence analyses, we have characterized the Fonni's Dog relative t...
ORGANISM(S): Canis lupus familiaris 
2016-06-10 | E-GEOD-83225 | biostudies-arrayexpress
UnknownTumor-specific polycistronic miRNA delivered by engineered exosomes for the treatment of glioblastoma.
Not available
S-EPMC10836765 | biostudies-literature
TranscriptomicsGene expression changes during development of sunitinib resistance in renal cell carcinoma patient derived xenografts
Transcriptome analysis was used to identify gene expression changes during development of sunitinib resistance in a renal cell carcinoma patient-derived xenograft (PDX) model. During the response phase, tumors exhibited a 91% reduction in volume, characterized by induction of TNFRSF1A, TNFAIP3, NFK...
ORGANISM(S): Homo sapiens 
2015-12-17 | E-GEOD-76068 | biostudies-arrayexpress
UnknownTop 10 priorities for future infertility research: an international consensus development study†  ‡.
Not available
S-EPMC7744161 | biostudies-literature
UnknownSymptoms and quality of life in patients with suspected angina undergoing CT coronary angiography: a randomised controlled trial.
Not available
S-EPMC5529983 | biostudies-literature
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