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While it has been clearly established that well positioned H2A.Z-containing nucleosomes flank the nucleosome depleted region (NDR) at the transcriptional start site (TSS) of active mammalian genes, how this chromatin-based information is transmitted through the cell cycle is unknown. We show here th...
ORGANISM(S): Mus musculus 
C. jejuni, a spiral-shaped gram-negative bacterium, is a leading bacterial cause of human foodborne illness. Acute disease is associated with C. jejuni invasion of the intestinal epithelium. Further, maximal host cell invasion requires the secretion of proteins termed Campylobacter invasion antige...
ORGANISM(S): Campylobacter jejuni 
PAM50 intrinsic subtype classification (Parker JS, Mullins M, Cheang MCU, et al: Supervised Risk Predictor of Breast Cancer Based on Intrinsic Subtypes. J Clin Oncol 27:1160-1167, 2009) was used for the Z1031 patient cohort. However, to account for potential technical biases such as differences in ...
ORGANISM(S): Homo sapiens 
Exercise stimulates systemic and tissue-specific adaptations that protect against lifestyle related diseases including obesity and type 2 diabetes. Exercise places high mechanical and energetic demands on contracting skeletal muscle, which require finely-tuned protein post-translational modification...
ORGANISM(S): Mus musculus (Mouse) Rattus norvegicus (Rat) 
2019-07-22 | PXD010452 | Pride
BTK substrate profile determined by treating digest KG-1 cell lysate with alkaline phosphatase followed by recombinant BTK. Samples were enriched with PolyMac phosphoenrichment kits prior to analysis. We have organized our uploaded files into three main folders: 1. BTK KALIP MS raw files: raw mass ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-11-22 | MSV000088429 | MassIVE
Limbal stem cells including epithelial and stromal/Mesenchymal stem cells that contribute to sustained corneal homeostasis, maintain their ability to act as self-renewal progenitor cells by virtue of their limbal niche and intercellular communication. Extracellular vehicles (EVs), including exosomes...
ORGANISM(S): Homo sapiens (Human) 
2023-10-23 | PXD040918 | Pride
BT474 cells stably expressing Alk5TD or vector (BT474-Alk5TD and BT474-pBMN, respectively) were compared for gene expression. Genes that were differentially expressed between the two cell lines were collected as the signature induced by Alk5TD expression. Keywords: Comparison of two cell types (BT47...
ORGANISM(S): Homo sapiens 
Mice which lack transcriptional corepressor RIP140 show muscle fibre-type switching and increased metabolic gene expression. Comparison between skeletal muscle tissue from wild type and RIP140-null mice fed normal or high-fat diet. Switched the diet when mice were 1 month old, then sampled at 3 mon...
ORGANISM(S): Mus musculus 
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