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GenomicsMonovalent and unpoised status of most genes in undifferentiated cell-enriched Drosophila testis
We use male gonads isolated from a Drosophila strain that allows us to obtain enough cells at their primitive status as the starting material to study the endogenous chromatin structure of undifferentiated cells using ChIP-seq. We integrate the ChIP-seq data with RNA-seq data that measures the trans...
ORGANISM(S): Drosophila melanogaster 
2010-04-16 | GSE19325 | GEO
UnknownCanine and feline parvoviruses can use human or feline transferrin receptors to bind, enter, and infect cells.
Not available
S-EPMC114880 | biostudies-literature
TranscriptomicsMonovalent and unpoised status of most genes in undifferentiated cell-enriched Drosophila testis
We use male gonads isolated from a Drosophila strain that allows us to obtain enough cells at their primitive status as the starting material to study the endogenous chromatin structure of undifferentiated cells using ChIP-seq. We integrate the ChIP-seq data with RNA-seq data that measures the trans...
ORGANISM(S): Drosophila melanogaster 
2010-04-16 | E-GEOD-19325 | biostudies-arrayexpress
ProteomicsPhosphoproteomic analysis of three exercise modalities in human skeletal muscle
To characterize phosphorylation-based signaling events across different exercise modalities we subjected eight healthy young men (age, 26.3±1.3 years; BMI, 23.5±0.7 kg/m2; maximal oxygen uptake (VO2 max), 42.6±1.5 ml/kg/min) that did not perform regular physical activity apart from local bicycling t...
ORGANISM(S): Homo sapiens (Human) 
2022-07-18 | PXD031049 | Pride
Skeletal muscle Phosphoproteomics Exericse 
UnknownRisk of harm in synthetic and biological intervention trials in patients with inflammatory arthritis: protocol for a metaepidemiological study focusing on contextual factors.
Not available
S-EPMC8422485 | biostudies-literature
ProteomicsProteomic and phosphoproteomic of C18ORF25 KO skeletal muscle following electrical contraction
We recently identified C18ORF25 as a new exercise-regulated phophoprotein. To investigate potential in vivo functions of C18ORF25, we used CRISPR/Cas9 to generate a whole-body knock-out (KO) mouse model on a C57BL/6J background. Proteomic analysis was performed to identify potental changes in the pr...
ORGANISM(S): Mus musculus (Mouse) 
2022-07-18 | PXD031101 | Pride
Proteomics Electrical contraction C18orf25 Skeletal muscles Phosphoproteomics 
ProteomicsPhosphoproteomics of rodent exercise models
Exercise stimulates systemic and tissue-specific adaptations that protect against lifestyle related diseases including obesity and type 2 diabetes. Exercise places high mechanical and energetic demands on contracting skeletal muscle, which require finely-tuned protein post-translational modification...
ORGANISM(S): Mus musculus (Mouse) Rattus norvegicus (Rat) 
2019-07-22 | PXD010452 | Pride
Skeletal muscle Signal transduction Exercise Phosphoproteomics 
TranscriptomicsRNA polymerase is poised for activation across the genome
Regulation of gene expression is integral to the development and survival of all organisms. Transcription begins with the assembly of a pre-initiation complex at the gene promoter, followed by initiation of RNA synthesis and the transition to productive elongation. In many cases, recruitment of RNA ...
ORGANISM(S): Drosophila melanogaster 
2007-11-11 | E-GEOD-6714 | biostudies-arrayexpress
UnknownAndrogen Deprivation and Sleep Disturbance: A Mixed Methods Pilot Study of Remote Assessment and Intervention.
Not available
S-EPMC9582038 | biostudies-literature
UnknownImmunologic signatures of response and resistance to nivolumab with ipilimumab in advanced metastatic cancer.
Not available
S-EPMC11349049 | biostudies-literature
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