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GenomicsH2A.Z inheritance during the cell cycle and its impact on promoter organization and dynamics [ChIP-seq]
While it has been clearly established that well positioned H2A.Z-containing nucleosomes flank the nucleosome depleted region (NDR) at the transcriptional start site (TSS) of active mammalian genes, how this chromatin-based information is transmitted through the cell cycle is unknown. We show here th...
ORGANISM(S): Mus musculus 
2012-11-23 | E-GEOD-41371 | biostudies-arrayexpress
ProteomicsPhosphoproteomic analysis of three exercise modalities in human skeletal muscle
To characterize phosphorylation-based signaling events across different exercise modalities we subjected eight healthy young men (age, 26.3±1.3 years; BMI, 23.5±0.7 kg/m2; maximal oxygen uptake (VO2 max), 42.6±1.5 ml/kg/min) that did not perform regular physical activity apart from local bicycling t...
ORGANISM(S): Homo sapiens (Human) 
2022-07-18 | PXD031049 | Pride
Skeletal muscle Phosphoproteomics Exericse 
ProteomicsThe exercise-regulated skeletal muscle phosphoproteome
Four healthy male volunteers (age: 24 - 27; BMI: 24.2 - 25.9 kg/m2) underwent a single bout of high-intensity bicycle exercise reaching a VO2 max approximately 95% with blood samples and muscle biopsies taken immediately pre- and post-exercise. Subjects reached 95% VO2 max in approximately 9 to 12 m...
ORGANISM(S): Homo sapiens (Human) 
2016-06-29 | PXD001543 | Pride
Skeletal muscle Phosphoproteomics Exericse 
UnknownA systematic investigation of human DNA preservation in medieval skeletons.
Not available
S-EPMC7588426 | biostudies-literature
ProteomicsA Comparison of Proteomic, Genomic, and Osteological Methods of Archaeological Sex Estimation
Proteomic sex estimation of human remains via liquid chromatography tandem mass spectrometry (LC- MS/MS) of sexually dimorphic amelogenin peptides in tooth enamel. The human remains analyzed in this study were recovered from two archaeological sites, Síi Túupentak (CA-ALA-565; ca. 200-600 cal BP) an...
ORGANISM(S): Homo sapiens (Human) 
2020-07-20 | PXD016076 | Pride
Amelogenin Archaeoforensics Sex estimation Proteomics Ancient dna Biomolecular archaeology 
TranscriptomicsH2A.Z inheritance during the cell cycle [expression array]
While it has been clearly established that well positioned H2A.Z-containing nucleosomes flank the nucleosome depleted region (NDR) at the transcriptional start site (TSS) of active mammalian genes 1,2, how this chromatin-based information is transmitted through the cell cycle is unknown. We show her...
ORGANISM(S): Mus musculus 
2012-11-23 | E-GEOD-41370 | biostudies-arrayexpress
ProteomicsPhosphoproteomic screening of exercise-like treatments reveals drug interactions regulating protein secretion
Exercise triggers skeletal muscle signalling pathways that modulate the release of circulating factors to cause systemic health benefits. Understanding these mechanisms could lead to better strategies for treating cardiometabolic diseases. We previously showed that acute exercise induces >1000 chang...
ORGANISM(S): Rattus norvegicus (Rat) 
2019-09-26 | PXD014322 | Pride
Phosphoproteomics Exercise Myotubes 
ProteomicsThe exercise-regulated skeletal muscle phosphoproteome
Four healthy male volunteers (age: 24 - 27; BMI: 24.2 - 25.9 kg/m2) underwent a single bout of high-intensity bicycle exercise reaching a VO2 max approximately 95% with blood samples and muscle biopsies taken immediately pre- and post-exercise. Subjects reached 95% VO2 max in approximately 9 to 12 m...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080777 | MassIVE
TranscriptomicsH2A.Z inheritance during the cell cycle
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2012-11-23 | E-GEOD-41091 | biostudies-arrayexpress
ProteomicsMultiplexed temporal quantification of the human plasma peptidome
The plasma peptidome contains the entire complement of low molecular weight endogenous peptides derived from secretion, protease activity and post-translational modifications and is a rich source of biomarkers and novel bioactives. To examine the utility of peptidomics we have examined the effects o...
ORGANISM(S): Homo sapiens (Human) 
2017-11-21 | PXD004781 | Pride
Peptidomics Exercise Peptidome Plasma 
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