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MetabolomicsExtreme genome diversity and cryptic speciation in a harmful algal bloom forming eukaryote

Harmful algal blooms (HABs) of the toxic haptophyte Prymnesium parvum are a recurrent problem in many inland and estuarine waters around the world. Strains of P. parvum vary in the toxins they produce and in other physiological traits associated with HABs, but the genetic basis ...

2023-04-26 | MTBLS5893 | MetaboLights
TranscriptomicsSpatially distinct neutrophil responses within the inflammatory lesions of pneumonic plague
During pneumonic plague, the bacterium Yersinia pestis elicits the development of inflammatory lung lesions that continue to expand throughout infection. This lesion development and persistence is poorly understood. Here, we examine spatially distinct regions of lung lesions using laser capture micr...
ORGANISM(S): Mus musculus 
2015-07-13 | E-GEOD-70819 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of fetal adrenocortical cells gene expression after 48 h ACTH treatment
Analysis of ACTH-regulation on adrenocortical cells at gene expression level. The hypothesis tested in the present study was that ACTH increases chronic cell growth and steroidogenesis in adrenal glands by changing the gene expression profile. Results provide important information on the changes of ...
ORGANISM(S): Homo sapiens 
2010-07-08 | E-GEOD-20675 | biostudies-arrayexpress
TranscriptomicsAn oncogenic Ezh2 mutation cooperates with particular genetic alterations to induce tumors in mice and redistributes H3K27m3 through the genome [RNA-seq]
B-cell lymphoma and melanoma harbor recurrent mutations in the gene encoding the EZH2 histone methyltransferase, but the carcinogenic role of these mutations is unclear. Here we describe a mouse model in which the most common somatic EZH2 gain-of-function mutation (Y646F in human, Y641F in the mous...
ORGANISM(S): Mus musculus 
2016-05-13 | E-GEOD-79035 | biostudies-arrayexpress
TranscriptomicsGene Expression Profiles of Head and Neck Squamous Cell Carcinoma (HNSCC) primary tumors
60 fresh frozen HNSCC from the University of North Carolina at Chapel Hill (UNC) were obtained from the UNC Tissue Procurement Facility under an IRB approved protocol. 55 tumor samples were collected from the primary tumor and five tumor samples were collected from a local recurrence at the primary ...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-686 | biostudies-arrayexpress
UnknownNutritional Status Predicts Fatty Acid Uptake from Fish and Soybean Oil Supplements for Treatment of Cancer-Related Fatigue: Results from a Phase II Nationwide Study.
Not available
S-EPMC8747418 | biostudies-literature
TranscriptomicsGenome-wide analysis of adult adrenocortical cells gene expression after 48 h ACTH treatment
Analysis of ACTH-regulation on adrenocortical cells at gene expression level. The hypothesis tested in the present study was that ACTH increases chronic cell growth and steroidogenesis in adrenal glands by changing the gene expression profile. Results provide important information of the response of...
ORGANISM(S): Homo sapiens 
2010-07-08 | E-GEOD-20669 | biostudies-arrayexpress
UnknownAdding Celecoxib With or Without Zoledronic Acid for Hormone-Naive Prostate Cancer: Long-Term Survival Results From an Adaptive, Multiarm, Multistage, Platform, Randomized Controlled Trial.
Not available
S-EPMC5455701 | biostudies-literature
UnknownTranslating the potential of the urine steroid metabolome to stage NAFLD (TrUSt-NAFLD): study protocol for a multicentre, prospective validation study.
Not available
S-EPMC10806741 | biostudies-literature
TranscriptomicsPolymicrobial sepsis-induced Myocardial Depression Transcriptional Profile
To describe the transcriptional changes associated with polymicrobial-sepsis induced myocardial depression in wild type and iNOS deficient mice. Keywords: myocardium, contractility, differential gene expression, nitric oxide synthase, infection We compared the transcriptional profile of C57/BL6 WT m...
ORGANISM(S): Mus musculus 
2010-11-17 | E-GEOD-9667 | biostudies-arrayexpress
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