Sort   by:  
 Page size 
TranscriptomicsIntegrated molecular pathway analysis informs a synergistic combination therapy targeting PTEN/PI3K and EGFR pathways for basal-like breast cancer.
Abstract BACKGROUND: The basal-like breast cancer (BLBC) subtype is characterized by positive staining for basal mammary epithelial cytokeratin markers, lack of hormone receptor and HER2 expression, and poor prognosis with currently no approved molecularly-targeted therapies. The oncogenic signaling...
ORGANISM(S): Homo sapiens 
2016-08-21 | E-GEOD-74667 | biostudies-arrayexpress
TranscriptomicsGene expression analysis of T-ALL cell lines treated with gamma-secretase inhibitor
Gain-of-function mutations in NOTCH1 are common in T-cell lymphoblastic leukemias making this receptor a promising target for drugs such as gamma-secretase inhibitors (GSI), which block a proteolytic cleavage required for NOTCH1 activation. However, the enthusiasm for these therapies has been temper...
ORGANISM(S): Homo sapiens 
2008-08-20 | E-GEOD-5716 | biostudies-arrayexpress
UnknownSignal and noise in metabarcoding data.
Not available
S-EPMC10174484 | biostudies-literature
TranscriptomicsBT549 cells with control or NFIL3 shRNA treatment
Transcriptional profiling with samples from BT549 cells that were infected with control or NFIL3 shRNA Two condition experiment: control (scr) shRNA (two replicates) and NFIL3 shRNA (two replicates)
ORGANISM(S): Homo sapiens 
2012-09-02 | E-GEOD-31425 | biostudies-arrayexpress
TranscriptomicsHEK293 cells with control or NFIL3 shRNA treatment
Transcriptional profiling with samples from HEK293 cells that were infected with control or NFIL3 shRNA Two condition experiment: control (scr) shRNA (six replicates) and NFIL3 shRNA (four replicates)
ORGANISM(S): Homo sapiens 
2012-09-02 | E-GEOD-31426 | biostudies-arrayexpress
TranscriptomicsDiminishment of NFIL3 by shRNA in HEK293 and BT549 cells
This SuperSeries is composed of the following subset Series: GSE31425: BT549 cells with control or NFIL3 shRNA treatment GSE31426: HEK293 cells with control or NFIL3 shRNA treatment Refer to individual Series
ORGANISM(S): Homo sapiens 
2012-09-02 | E-GEOD-31427 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human gamma-secretase inhibitor-sensitive and -resistant T-ALL cell lines
Gain-of-function mutations in NOTCH1 are common in T-cell lymphoblastic leukemias making this receptor a promising target for drugs such as gamma-secretase inhibitors, which block a proteolytic cleavage required for NOTCH1 activation. However, the enthusiasm for these therapies has been tempered by ...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-5682 | biostudies-arrayexpress
UnknownSafety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial.
Not available
S-EPMC7674972 | biostudies-literature
UnknownWho, if anyone, may benefit from a total hip arthroplasty after a displaced femoral neck fracture?: a post hoc subgroup analysis of the HEALTH trial.
Not available
S-EPMC9422900 | biostudies-literature
UnknownSingle-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials.
Not available
S-EPMC7894131 | biostudies-literature
Sort   by:  
 Page size