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ProteomicsAssembly and cell-free expression of a partial genome for the synthetic cell
We designed and assembled a multicistronic DNA plasmid containing multiple genes that are relevant for a synthetic cell. This partial minimal synthetic genome was expressed in the recombinant PURE system. Cell-free biosynthesis of all encoded proteins was validated by liquid chromatography-mass spec...
ORGANISM(S): Anaplasma marginale Aequorea victoria Bacillus phage phi29 Escherichia coli 
2026-10-28 | PXD069407 | Pride
Partial genome Cell-free biosynthesis Label-free quantification Synthetic cell Lc-ms/ms 
TranscriptomicsFull and partial genome-wide assembly and disassembly of the yeast transcription machinery in response to heat shock
Eukaryotic genes are controlled by sequence-specific DNA-binding proteins, chromatin regulators, general transcription factors, and elongation factors. Here we examine the genome-wide location of representative members of these groups and their redistribution when the Saccharomyces cerevisiae genom...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-10 | E-GEOD-2488 | biostudies-arrayexpress
TranscriptomicsIdentification of Ccr4-Not complex as a regulator of transition from partial to genuine iPS cells
Partial induced pluripotent cells (iPSCs) are cell lines strayed from normal route from somatic cells to iPSCs and are immortalized. Mouse partial iPSCs are able to convert to real iPSCs by the exposure to 2i condition using MAPK and GSK3? inhibitors. However, the molecular mechanisms of this conver...
ORGANISM(S): Mus musculus 
2014-01-07 | E-GEOD-44339 | biostudies-arrayexpress
GenomicsGenome wide analysis of liver histone H3K9 acetylation after partial hepatectomy in glucose-treated and control mice.
We report the results of AcH3K9 ChIP-Seq on regenerating liver harvested 12 h after partial hepatectomy (PH) from mice treated with supplemental parenteral dextrose (to delay onset of PH-induced hypoglycemia) or vehicle (as control). Examination of the effect of delaying PH-induced hypoglycemia on h...
ORGANISM(S): Mus musculus 
2016-02-09 | E-GEOD-71496 | biostudies-arrayexpress
TranscriptomicsProstates of rats with induced partial bladder outlet obstruction and the effect of Eviprostat on those changes
Prostatic inflammation plays a role in the progression of benign prostatic hyperplasia (BPH). Eviprostat is an antiinflammatory and antioxidant phytotherapeutic agent widely used to treat lower urinary tract symptoms in BPH. However, because Eviprostat is a mixture of compounds from multiple natural...
ORGANISM(S): Rattus norvegicus 
2010-04-09 | E-GEOD-16063 | biostudies-arrayexpress
TranscriptomicsMurine liver tissues: WT and Wip1 KO mice after Partial Hepatectomy at 24h and 36 h.
Transcriptional profiling of mouse liver tissues comparing Wild type liver tissues with Wip1 KO mice liver tissues after Partial Hepatectomy at 24h and 36 h. WT vs. Wip1 KO tissues after Partial Hepatectomy at 24h and 36 h .
ORGANISM(S): Mus musculus 
2014-07-03 | E-GEOD-59023 | biostudies-arrayexpress
TranscriptomicsHepatic gene expression during liver regeneration in response to partial hepatectomy: early time points (0.5h,1h,2h,4h)
The process of liver regeneration can be divided into a series of stages that include initial inductive or priming events through cellular mitosis. Following two-thirds liver resection, the liver undergoes the “priming” phase, in which cytokines TNF-a and IL-6 activate their respective receptors in...
ORGANISM(S): Mus musculus 
2011-02-16 | E-GEOD-20425 | biostudies-arrayexpress
GenomicsActivated sludge for partial nitritation
Activated sludge for partial nitritation Metagenomic assembly
PRJNA779449 | ENA
GenomicsA Single Complex Agpat2 Allele In A Patient With Partial Lipodystrophy
Genetic lipodystrophies are a group of rare syndromes associated with major metabolic complications - including severe insulin resistance, type 2 diabetes mellitus, and hypertriglyceridemia - which are classified according to the distribution of adipose tissue. Lipodystrophies can be present at birt...
EGAS00001003177 | EGA
TranscriptomicsGenotyping of human diagnosic AML samples reveals frequent partial uniparental disomy due to somatic recombination in acute myeloid leukemias
Genome-wide analysis of single nucleotide polymorphisms in 64 acute myeloid leukemias has revealed that 20% exhibited large regions of homozygosity that could not be accounted for by visible chromosomal abnormalities in the karyotype. Further analysis confirmed that these patterns were due to partia...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7490 | biostudies-arrayexpress
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