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UnknownEarly doors (Edo) mutant mouse reveals the importance of period 2 (PER2) PAS domain structure for circadian pacemaking.
Not available
S-EPMC4791021 | biostudies-literature
ProteomicsA conserved chronobiological complex times C. elegans development; map in vivo LIN-42 phosphorylation sites
The mammalian PAS-domain protein PERIOD (PER) and its C. elegans orthologue LIN-42 have been proposed to constitute an evolutionary link between two distinct, circadian and developmental, timing systems. However, while the function of PER in animal circadian rhythms is well understood molecularly an...
ORGANISM(S): Caenorhabditis elegans 
2025-10-10 | PXD058598 | Pride
Kin-20 Lin-42 Ck1bd Phosphorylation Pas-domain protein period C. elegans development 
ProteomicsA conserved chronobiological complex times C. elegans development; map LIN-42 interacting proteins
The mammalian PAS-domain protein PERIOD (PER) and its C. elegans orthologue LIN-42 have been proposed to constitute an evolutionary link between two distinct, circadian and developmental, timing systems. However, while the function of PER in animal circadian rhythms is well understood molecularly an...
ORGANISM(S): Caenorhabditis elegans 
2025-10-10 | PXD058601 | Pride
Kin-20 Lin-42 Ck1bd Phosphorylation Pas-domain protein period C. elegans development 
UnknownKidA, a multi-PAS domain protein, tunes the period of the cyanobacterial circadian oscillator.
Not available
S-EPMC9478674 | biostudies-literature
UnknownRedox properties and PAS domain structure of the Escherichia coli energy sensor Aer indicate a multistate sensing mechanism.
Not available
S-EPMC9668731 | biostudies-literature
UnknownStructure of an enclosed dimer formed by the Drosophila period protein.
Not available
S-EPMC3252215 | biostudies-literature
TranscriptomicsProtein affects gene expression and prevents lipid accumulation in the liver in mice
Obesity and associated increased prevalence of non-alcoholic fatty liver (NAFLD) disease is suggested to be positively modulated by a high protein (HP) diet in humans and rodents. The aim was to detect mechanisms by which a HP diet prevents hepatic lipid accumulation by means of transcriptomics. To ...
ORGANISM(S): Mus musculus 
2012-11-21 | E-GEOD-37897 | biostudies-arrayexpress
TranscriptomicsEffects of diet and age on canine skeletal muscle (biceps femoris) gene expression
Aging animals display a decline in a multitude of physical and physiological functions, including muscle function and strength. Muscle gene expression in dogs has been evaluated for a few select genes under pathogenic or varying dietary conditions, but global gene expression profiles of aged animal...
ORGANISM(S): Canis lupus familiaris 
2010-05-22 | E-GEOD-12502 | biostudies-arrayexpress
TranscriptomicsEffects of diet and age on canine colon tissue gene expression
Aging alters gastrointestinal morphology, microbiota, and functionality, and is associated with increased incidence of intestinal disease. The mechanisms that contribute to these changes are poorly described. Gene expression in dogs has been evaluated for a few select genes under pathogenic or var...
ORGANISM(S): Canis lupus familiaris 
2010-08-01 | E-GEOD-20557 | biostudies-arrayexpress
TranscriptomicsEffects of chronic hypoxia on Duchenne Muscular Dystrophy Drosophila melanogaster model
In order to understand the chronic hypoxia (CH) effect upon the absence of dystrophin, Drosophila melanogaster wild type and the model for DMD (dmDys), in which all dystrophins expression was knocked out by iRNA, were exposed to high altitude hypoxia (hypobaric hypoxia) during a 16-day climbing per...
ORGANISM(S): Drosophila melanogaster 
2010-07-31 | E-GEOD-15879 | biostudies-arrayexpress
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