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Transcriptomics3' mRNA-seq of human Ma-Mel-47 (melanoma) and Panc89 (PDAC) cells treated with the USP7 degraders NK266 and NK250, respectively, for 72 h.
3' mRNA-seq was used to study the effects of USP7 degradation by the degraders NK266 and NK250 on gene expression in a human melanoma and PDAC cell line, respectively.
ORGANISM(S): Homo sapiens 
2026-03-27 | E-MTAB-16302 | biostudies-arrayexpress
TranscriptomicsAffymetrix SNP array data of melanoma cell lines from lymph node metastates
Melanoma recurrence frequently occurs after a latency period of several years. In vivo studies demonstrated that tumor cells overcoming latency show a T cell-edited phenotype, suggesting a relevant role for CD8+ T cells in maintaining metastatic latency. Here, in a patient model of multiple recurren...
ORGANISM(S): Homo sapiens 
2016-07-27 | E-GEOD-80736 | biostudies-arrayexpress
ModelsLiu2019 - Logistic Regression models to predict intrinsic resistance to anti-PD1 ICB in Ipilimumab treated and Ipilimumab naive patients with metastatic melanoma.
In this comprehensive study, the authors have developed concise models integrating clinical, genomic and transcriptomic features to predict intrinsic resistance to anti-PD1 Immune Checkpoint Blockade (ICB) treatment in individual tumors. It's important to note that their validation was performed in ...
2023-11-17 | MODEL2310150001 | BioModels
Machine Learning Model FAIR-AIML 
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