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Transcriptomics17beta-estradiol (E2)-regulated gene expression across time in estrogen-dependent and estrogen deprivation-resistant MCF-7-derived breast cancer cell lines.
A series of MCF-7 variants were previously developed that are either estrogen-dependent for growth (MCF-7:WS8 cells), or resistant to estrogen deprivation and refractory (MCF-7:2A) or sensitive (MCF-7:5C) to E2-induced apoptosis. To identify genes associated with E2-induced apoptosis, estrogen depri...
ORGANISM(S): Homo sapiens 
2011-11-21 | E-GEOD-29917 | biostudies-arrayexpress
TranscriptomicsHypoxia-induced modulation of gene expression in human adipocytes - A microarray study
Obesity is characterised by expansion of white adipose tissue, accompanied by an inflamatory response. It has been proposed that the inflammatory state observed may be linked to relative hypoxia in clusters of adipocytes distant from vasculature. Adipose tissue hypoxia has been observed in both an...
ORGANISM(S): Homo sapiens 
2012-03-09 | E-GEOD-34007 | biostudies-arrayexpress
UnknownHMGB1 targeting by ethyl pyruvate suppresses malignant phenotype of human mesothelioma.
Not available
S-EPMC5410252 | biostudies-literature
UnknownBiological Mechanisms and Clinical Significance of BAP1 Mutations in Human Cancer.
Not available
S-EPMC8006752 | biostudies-literature
UnknownInvolvement of Heparanase in the Pathogenesis of Mesothelioma: Basic Aspects and Clinical Applications.
Not available
S-EPMC6186523 | biostudies-literature
UnknownInhibition of the spindle assembly checkpoint kinase Mps-1 as a novel therapeutic strategy in malignant mesothelioma.
Not available
S-EPMC5690838 | biostudies-literature
TranscriptomicsExpression data from mesothelial (LP9) and mesothelioma cells (HMESO) inhibited for extracellular-regulated kinase (ERK) 1, 2, or 5
Extracellular-regulated kinases (ERK1/2 and 5) are known to play important roles in growth and drug resistance of various cancers. Here we show roles of inhibition of ERK1, ERK2, or ERK5 on gene expression profiles of epithelioid malignant mesothelioma (MM) cells (HMESO). Untransfected human mesothe...
ORGANISM(S): Homo sapiens 
2010-05-08 | E-GEOD-21750 | biostudies-arrayexpress
UnknownHeterozygous germline <i>BLM</i> mutations increase susceptibility to asbestos and mesothelioma.
Not available
S-EPMC7776606 | biostudies-literature
UnknownHigh-density array-CGH with targeted NGS unmask multiple noncontiguous minute deletions on chromosome 3p21 in mesothelioma.
Not available
S-EPMC5127333 | biostudies-literature
TranscriptomicsComplex Patterns of Altered MicroRNA Expression during the Adenoma-Adenocarcinoma Sequence for Microsatellite-stable Colorectal Cancer
We searched the database of the Department of Pathology at The University of Texas MD Anderson Cancer Center and selected 21 patients who had invasive microsatellite-stable colorectal adenocarcinoma arising from a pre-existing adenoma and adjacent non-neoplastic mucosa in a resection specimen to per...
ORGANISM(S): Homo sapiens 
2012-08-17 | E-MTAB-813 | biostudies-arrayexpress
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