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TranscriptomicsAnalysis of wildtype and Xbp1-deficient hematopoietic progenitor cell transcriptomes
Purpose: The goals of this study are to assess the transcriptional networks governed by the transcription factor XBP1 in lineage-uncommitted myeloid progenitors and in eosinophil-committed myeloid progenitors. Methods: mRNA profiles of FACS-purified granulocyte-macrophage progenitors (GMPs) from X...
ORGANISM(S): Mus musculus 
2015-07-06 | E-GEOD-65753 | biostudies-arrayexpress
TranscriptomicsGene expression changes in Peripheral Blood Mononuclear cells (PBMC) induced by physical activity
Gene expression changes in Peripheral Blood Mononuclear cells (PBMC) induced by physical activity was investigated in sedentary middle-aged men (mean age 52.6 years and BMI 29.1) who undertook a 24-week physical activity programme with blood sampling in the pre-exercise period , at the end of 24-w...
ORGANISM(S): Homo sapiens 
2010-08-03 | E-GEOD-12385 | biostudies-arrayexpress
TranscriptomicsEffect of IL6 level on gene expression changes in Peripheral Blood Mononuclear cells (PBMC) induced by physical activity
A number of chronic, age-related diseases are associated with elevated markers of inflammation such as interleukin-6 (IL-6). In this study, we investigated the hypothesis that sedentary individuals with disparate basal serum IL-6 respond differentially to a structured physical activity programme. Ge...
ORGANISM(S): Homo sapiens 
2010-08-03 | E-GEOD-12384 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Neisseria meningitidis knock out mutant of snC transcriptional regulator compared to parent strains
Knock out mutant of asnC transcriptional regulator (NMB0573) in N. meningitidis MC58 compared to parent strains (capsule deletion mutant) grown in normal bacterial solid media plate conditions.
ORGANISM(S): Neisseria meningitidis 
2007-04-05 | E-MEXP-925 | biostudies-arrayexpress
TranscriptomicsLong-Term Programming of Antigen-Specific Immunity from Gene Expression Signatures in the PBMC of Rhesus Macaques Immunized with an SIV DNA Vaccine
The primary objective of this study was to evaluate response to a SIV DNA-based vaccine that was adminstered via vivo electroporation (EP) in rhesus macaques to further understand the molecular correlates of protection against SIV. In this study, rhesus macaques were immunized with a DNA vaccine inc...
ORGANISM(S): Macaca mulatta 
2012-02-15 | E-GEOD-35816 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human monocytic cells THP-1 stimulated with LPS (10ng/ml) in presence or absence of LL-37 (5 ug/ml), as well as with the peptide alone, for 4 hours
The objective of the study was to evaluate transcriptional response of endotoxin-stimulated human monocytic cells in presence or absence of host defense peptide LL-37 at low physiologically relevant concentrations. Human monocytic cells THP-1 were stimulated with LPS (10ng/ml) in presence or absenc...
ORGANISM(S): Homo sapiens 
2006-12-07 | E-FPMI-6 | biostudies-arrayexpress
GenomicsH2AV_9751.S2.GFP.RNAi.Solexa
modENCODE_submission_5596 This submission comes from a modENCODE project of Gary Karpen. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: The goal of these experiments are to a) validate/confirm the locations of 125 chromosomal proteins across the Drosophila mela...
ORGANISM(S): Drosophila melanogaster 
2013-11-01 | E-GEOD-51991 | biostudies-arrayexpress
GenomicsH2AV_9751.S2.H2AV_RNAi.Solexa
modENCODE_submission_5595 This submission comes from a modENCODE project of Gary Karpen. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: The goal of these experiments are to a) validate/confirm the locations of 125 chromosomal proteins across the Drosophila mela...
ORGANISM(S): Drosophila melanogaster 
2013-11-01 | E-GEOD-51990 | biostudies-arrayexpress
TranscriptomicsBEAF-HB.BG3.CP190_RNAi
modENCODE_submission_3664 This submission comes from a modENCODE project of Gary Karpen. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: The goal of these experiments are to validate and confirm the locations of 125 chromosomal proteins across the Drosophila mel...
ORGANISM(S): Drosophila melanogaster 
2011-10-12 | E-GEOD-32774 | biostudies-arrayexpress
TranscriptomicsCP190-HB.BG3.LacZ_RNAi
modENCODE_submission_3668 This submission comes from a modENCODE project of Gary Karpen. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: The goal of these experiments are to validate and confirm the locations of 125 chromosomal proteins across the Drosophila mel...
ORGANISM(S): Drosophila melanogaster 
2011-10-12 | E-GEOD-32778 | biostudies-arrayexpress
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