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TranscriptomicsMouse colon expression in wild type and STAT5b deficient mice
Regulation of epithelial barrier function is dependent upon precise control of cell survival and activation of inflammatory pathways in response to the enteric flora. These experiments tested differential colon gene expression relative to these pathways in wild type and STAT5b deficient mice. Keywor...
ORGANISM(S): Mus musculus 
2010-05-25 | E-GEOD-8942 | biostudies-arrayexpress
ProteomicsPlasmepsin X activates function of the PCRCR complex in P. falciparum by processing PfRh5 for binding to basigin and invasion of human erythrocytes
Plasmodium falciparum causes the most severe form of malaria in humans. The protozoan parasite develops within erythrocytes to mature schizonts, that contain more than 16 merozoites, which egress and invade fresh erythrocytes. The aspartic protease plasmepsin X (PMX), processes proteins and protease...
ORGANISM(S): Plasmodium falciparum (isolate 3D7) 
2023-04-05 | PXD039646 | Pride
Malaria Plasmepsin x Ip-ms Pcrcr 
ProteomicsFunction of the Rh5 complex in invasion of human erythrocytes
The most severe form of malaria is caused by Plasmodium falciparum. These parasites invade human erythrocytes and an essential step in this process involves the ligand PfRh5, which forms a complex with CyRPA and PfRipr (RCR complex) and binds basigin on the host cell. We identified a heteromeric dis...
ORGANISM(S): Plasmodium falciparum (isolate 3D7) 
2022-12-14 | PXD036746 | Pride
Pfripr Basigin Ptramp Human erythrocytes Invasion complex Pfrh5 Malaria Css P. falciparum 
UnknownComplementary value of molecular, phenotypic, and functional aging biomarkers in dementia prediction.
Not available
S-EPMC11979055 | biostudies-literature
UnknownDiscovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotherapy Tool Compounds.
Not available
S-EPMC8040257 | biostudies-literature
UnknownCognitive deficits, clinical variables, and white matter microstructure in schizophrenia: a multisite harmonization study.
Not available
S-EPMC10538303 | biostudies-literature
UnknownDeterminants of cognitive and brain resilience to tau pathology: a longitudinal analysis.
Not available
S-EPMC10473572 | biostudies-literature
UnknownIncreased brain-predicted aging in treated HIV disease.
Not available
S-EPMC5379929 | biostudies-literature
UnknownSex-specific modulation of amyloid-β on tau phosphorylation underlies faster tangle accumulation in females.
Not available
S-EPMC10994548 | biostudies-literature
UnknownInsulin-like growth factor binding protein-2 in at-risk adults and autopsy-confirmed Alzheimer brains.
Not available
S-EPMC11068109 | biostudies-literature
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