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UnknownNeutralization of Plasmodium falciparum merozoites by antibodies against PfRH5.
Not available
S-EPMC3872115 | biostudies-literature
UnknownErythrocyte binding protein PfRH5 polymorphisms determine species-specific pathways of Plasmodium falciparum invasion.
Not available
S-EPMC2677973 | biostudies-literature
ProteomicsFunction of the Rh5 complex in invasion of human erythrocytes
The most severe form of malaria is caused by Plasmodium falciparum. These parasites invade human erythrocytes and an essential step in this process involves the ligand PfRh5, which forms a complex with CyRPA and PfRipr (RCR complex) and binds basigin on the host cell. We identified a heteromeric dis...
ORGANISM(S): Plasmodium falciparum (isolate 3D7) 
2022-12-14 | PXD036746 | Pride
Pfripr Basigin Ptramp Human erythrocytes Invasion complex Pfrh5 Malaria Css P. falciparum 
UnknownAssessing the functional impact of PfRh5 genetic diversity on ex vivo erythrocyte invasion inhibition.
Not available
S-EPMC7838290 | biostudies-literature
ProteomicsPlasmepsin X activates function of the PCRCR complex in P. falciparum by processing PfRh5 for binding to basigin and invasion of human erythrocytes
Plasmodium falciparum causes the most severe form of malaria in humans. The protozoan parasite develops within erythrocytes to mature schizonts, that contain more than 16 merozoites, which egress and invade fresh erythrocytes. The aspartic protease plasmepsin X (PMX), processes proteins and protease...
ORGANISM(S): Plasmodium falciparum (isolate 3D7) 
2023-04-05 | PXD039646 | Pride
Malaria Plasmepsin x Ip-ms Pcrcr 
UnknownMultiprotein complex between the GPI-anchored CyRPA with PfRH5 and PfRipr is crucial for Plasmodium falciparum erythrocyte invasion.
Not available
S-EPMC4313826 | biostudies-literature
UnknownVaccine-induced human monoclonal antibodies to PfRH5 show broadly neutralizing activity against P. falciparum clinical isolates.
Not available
S-EPMC11502735 | biostudies-literature
UnknownRational structure-guided design of a blood stage malaria vaccine immunogen presenting a single epitope from PfRH5.
Not available
S-EPMC11473951 | biostudies-literature
UnknownEnhancing blockade of Plasmodium falciparum erythrocyte invasion: assessing combinations of antibodies against PfRH5 and other merozoite antigens.
Not available
S-EPMC3493472 | biostudies-literature
UnknownStructure-guided insights into potential function of novel genetic variants in the malaria vaccine candidate PfRh5.
Not available
S-EPMC9653458 | biostudies-literature
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