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MetabolomicsDietary restriction of cysteine and methionine sensitizes gliomas to ferroptosis and induces alterations in energetic metabolism

Ferroptosis is mediated by lipid peroxidation of phospholipids containing polyunsaturated fatty acyl moieties. Glutathione, the key cellular antioxidant capable of inhibiting lipid peroxidation via the activity of the enzyme glutathione peroxidase 4 (GPX-4), is generated directly from the sulfur-...

2023-01-11 | MTBLS5959 | MetaboLights
GenomicsMMP-seq tumor samples (FASTQ) - samples
MMP-seq tumor samples (FASTQ)
EGAD00001001108 | EGA
GenomicsMMP-seq cell lines (FASTQ) - samples
MMP-seq cell lines (FASTQ)
EGAD00001001107 | EGA
GenomicsMMP-seq tumor samples, UDG treated (FASTQ) - samples
MMP-seq tumor samples, UDG treated (FASTQ)
EGAD00001001104 | EGA
GenomicsHigh-throughput Detection of Clinically Relevant Mutations in Archived Tumor Samples By Multiplexed PCR and Next Generation Sequencing
PURPOSE: Tailoring cancer treatment to tumor molecular characteristics promises to make personalized medicine a reality. However, reliable genetic profiling of archived clinical specimens has been hindered by limited sensitivity and high false positive rates. Here, we describe a novel methodology, M...
EGAS00001000674 | EGA
UnknownCannabidiol attenuates cardiac dysfunction, oxidative stress, fibrosis, and inflammatory and cell death signaling pathways in diabetic cardiomyopathy.
Not available
S-EPMC3026637 | biostudies-literature
UnknownThe systematic assessment of completeness of public metadata accompanying omics studies in the Gene Expression Omnibus.
Not available
S-EPMC12265520 | biostudies-literature
UnknownPreliminary model assessing the cost-effectiveness of preoperative chlorhexidine mouthwash at reducing postoperative pneumonia among abdominal surgery patients in South Africa.
Not available
S-EPMC8360544 | biostudies-literature
UnknownMachine learning derived retinal pigment score from ophthalmic imaging shows ethnicity is not biology.
Not available
S-EPMC11696055 | biostudies-literature
UnknownEffects of Influenza Vaccination in the United States During the 2017-2018 Influenza Season.
Not available
S-EPMC7188082 | biostudies-literature
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