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ProteomicsPanomics reveals patient individuality as the major driver of colorectal cancer progression
Colorectal cancer (CRC) is one of the most prevalent cancers, with over one million new cases per year. Overall, prognosis of CRC largely depends on the disease stage and metastatic status. As precision oncology for patients with CRC continues to improve, this study aimed to integrate genomic, trans...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD036434 | Pride
Tumor heterogeneity Multi-omics Colorectal cancer Patient individuality 
TranscriptomicsIndividuality and variation in gene expression patterns in human blood.
We carried out a survey of the variation in gene expression patterns in the blood of healthy individuals, by using cDNA microarrays. Our results revealed a surprising consistency in these patterns, but also evidence of distinct patterns of interindividual and temporal variation. Some features of v...
ORGANISM(S): Homo sapiens 
2005-11-22 | E-GEOD-3649 | biostudies-arrayexpress
GenomicsIndividuality and variation of personal regulomes in human T cells
We surveyed the variation and dynamics of active regulatory elements genome-wide in CD4+ T cells, using Assay of Transposase Accessible Chromatin with sequencing (ATAC-seq) in longitudinal samples from healthy volunteers and during T cell activation. We created robust pipelines that enable accurate ...
ORGANISM(S): Homo sapiens 
2015-06-23 | E-GEOD-60682 | biostudies-arrayexpress
UnknownPanomics reveals patient individuality as the major driver of colorectal cancer progression.
Not available
S-EPMC9869555 | biostudies-literature
UnknownHigh individuality of respiratory bacterial communities in a large cohort of adult cystic fibrosis patients under continuous antibiotic treatment.
Not available
S-EPMC4324987 | biostudies-literature
ProteomicsThunder-DDA-PASEF enables high-coverage immunopeptidomics and is boosted by MS2Rescore with novel MS2PIP timsTOF fragmentation prediction model
Human leukocyte antigen (HLA) class I peptide ligands (HLAIps) are key targets for developing vaccines and immunotherapies against infectious pathogens or cancer cells. Identifying HLAIps is challenging due to their high diversity, low abundance, and patient individuality. Here, we developed a highl...
ORGANISM(S): Homo Sapiens (human) 
2024-03-18 | PXD040385 | JPOST Repository
UnknownOptimizing Patient Education of Oncology Medications: A Patient Perspective.
Not available
S-EPMC6785581 | biostudies-literature
ModelsBucher2011_Atorvastatin_Metabolism
This is the model of atorvastatin metabolism in hepaitc cells described in the article: A systems biology approach to dynamic modeling and inter-subject variability of statin pharmacokinetics in human hepatocytes Joachim Bucher , Stephan Riedmaier , Anke Schnabel , Katrin Marcus , G...
2024-09-02 | BIOMD0000000328 | BioModels
UnknownLongitudinal study of recurrent metastatic melanoma cell lines underscores the individuality of cancer biology.
Not available
S-EPMC3989423 | biostudies-literature
TranscriptomicsTranscription profiling of human healthy peripheral blood from different individuals
We carried out a survey of the variation in gene expression patterns in the blood of healthy individuals, by using cDNA microarrays. Our results revealed a surprising consistency in these patterns, but also evidence of distinct patterns of interindividual and temporal variation. Some features of v...
ORGANISM(S): Homo sapiens 
2005-10-05 | E-SMDB-1819 | biostudies-arrayexpress
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